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DcR1 抗体

TNFRSF10C 适用: 人 Func 宿主: 小鼠 Monoclonal B-D44 unconjugated
产品编号 ABIN1106169
发货至: 中国
  • 抗原 See all DcR1 (TNFRSF10C) 抗体
    DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
    适用
    • 60
    • 7
    • 7
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    宿主
    • 41
    • 24
    • 1
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    小鼠
    克隆类型
    • 43
    • 24
    单克隆
    标记
    • 33
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    This DcR1 antibody is un-conjugated
    应用范围
    • 40
    • 24
    • 24
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    Functional Studies (Func)
    特异性
    Recognizes the soluble antigen. Recognizes the 75-90 kDa protein.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ion Exchange Chromatography.
    过滤
    0.22 μm filtered
    免疫原
    Recombinant Human TRAIL R3/Fc chimera. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
    克隆位点
    B-D44
    亚型
    IgG1
    Top Product
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  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.
    储存液
    Without preservative
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
    别名
    CD263 / TRAILR3 (TNFRSF10C 产品)
    别名
    CD263 antibody, DCR1 antibody, DCR1-TNFR antibody, LIT antibody, TRAIL-R3 antibody, TRAILR3 antibody, TRID antibody, TNFRSF10C antibody, TNF receptor superfamily member 10c antibody, TNFRSF10C antibody
    背景
    TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).Synonyms: Antagonist decoy receptor for TRAIL/Apo-2L, DCR1, Decoy TRAIL receptor without death domain, Decoy receptor 1, LIT, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TNFRSF10C, TRAIL receptor 3, TRAIL-R3, TRID, Trail receptor without an intracellular domain, Tumor necrosis factor receptor superfamily member 10C
    基因ID
    8794
    NCBI登录号
    NP_003832
    UniProt
    O14798
    途径
    Apoptosis
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