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CD21 抗体

CR2 适用: 人 IF, IHC (fro) 宿主: 小鼠 Monoclonal 4C5 unconjugated
产品编号 ABIN1106058
发货至: 中国
  • 抗原 See all CD21 (CR2) 抗体
    CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD21 antibody is un-conjugated
    应用范围
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    Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ig Fraction
    免疫原
    A BALB/c mouse was immunized subcutaneously in its footpads with fragments of a Human tonsil. After fusing the lymphocytes from the popliteal lymph nodes of this mouse with murine SP2/0 myeloma cells
    克隆位点
    4C5
    亚型
    IgG2a
    Top Product
    Discover our top product CR2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    60 μg Ig/ml
    缓冲液
    0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for Three months or (in aliquots) at -20 °C for longer.
  • 抗原
    CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
    别名
    CD21 (CR2 产品)
    别名
    C3DR antibody, CD21 antibody, CR antibody, CVID7 antibody, SLEB9 antibody, Cd21 antibody, cd21 antibody, CR1 antibody, CR1-L antibody, CR2 antibody, complement C3d receptor 2 antibody, complement C3b/C4b receptor 1 (Knops blood group) antibody, CR2 antibody, Cr2 antibody, CR1 antibody
    背景
    CD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular Dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. Complement receptor (CR) type 2 (CR2/ CD21) is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigen.Synonyms: C3DR, C3d receptor, CR2, Complement C3d receptor, Complement receptor type 2, Dendritic Cell Marker, EBV Receptor, Epstein-Barr virus receptor
    分子量
    145 kDa
    基因ID
    9606
    UniProt
    P20023
    途径
    Complement System
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