电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PTPRJ 抗体 (N-Term)

PTPRJ 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-CD148-05 unconjugated
产品编号 ABIN1105887
发货至: 中国
  • 抗原 See all PTPRJ 抗体
    PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
    抗原表位
    • 12
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-444, N-Term
    适用
    • 46
    • 17
    • 13
    • 1
    • 1
    宿主
    • 31
    • 19
    小鼠
    克隆类型
    • 31
    • 18
    单克隆
    标记
    • 23
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTPRJ antibody is un-conjugated
    应用范围
    • 36
    • 16
    • 15
    • 13
    • 10
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein-A affinity chromatography
    纯度
    > 95 % pure by SDS-PAGE
    免疫原
    Human recombinant CD148 (amino acids 1-444)
    克隆位点
    MEM-CD148-05
    亚型
    IgG2b
    Top Product
    Discover our top product PTPRJ Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), approx. pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
    别名
    CD148 / PTPRJ (PTPRJ 产品)
    别名
    HAAP antibody, CD148 antibody, DEP1 antibody, HPTPeta antibody, R-PTP-ETA antibody, SCC1 antibody, AI450271 antibody, BET antibody, Byp antibody, DEP-1 antibody, PTPbeta2 antibody, Ptpb2 antibody, RPTPJ antibody, Scc-1 antibody, Scc1 antibody, PTPRJ antibody, acid phosphatase 1 antibody, protein tyrosine phosphatase, receptor type J antibody, protein tyrosine phosphatase, receptor type, J antibody, ACP1 antibody, PTPRJ antibody, Ptprj antibody, EUBREC_2762 antibody
    背景
    CD148 (also known as HPTP-eta or DEP-1) is a transmembrane protein tyrosin phosphatase containing eight fibronectin type III extracellular domains. This protein is known to inhibit transduction of mitogenic signals in non-hematopoietic cells (fibroblasts, epithelial cells), and signal transduction downstream of T cell receptor, however, it also augments immunoreceptor signaling in B cells and macrophages via dephosphorylating C-terminal tyrosine of Src-family tyrosine kinases. CD148 expression increases after in vitro activation of peripheral blood leucocytes. It can be also used as marker of the most mature human thymocytes, and leukemic cells corresponding to this stadium of thymocyte differentiation. In contrast, in mice the CD148 expression sharply drops through the double positive stage to the single positive thymocytes.Synonyms: DEP-1, DEP1, HPTP eta, Protein-tyrosine phosphatase eta, Protein-tyrosine phosphatase receptor type J, R-PTP-J, R-PTP-eta, Receptor-type tyrosine-protein phosphatase eta
    基因ID
    5795
    NCBI登录号
    NP_002834
    UniProt
    Q12913
    途径
    EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
客服