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C3AR1 抗体

C3AR1 适用: 人 IHC (fro) 宿主: 小鼠 Monoclonal 17 unconjugated
产品编号 ABIN1105615
发货至: 中国
  • 抗原 See all C3AR1 抗体
    C3AR1 (Complement Component 3a Receptor 1 (C3AR1))
    适用
    • 39
    • 16
    • 10
    宿主
    • 30
    • 18
    小鼠
    克隆类型
    • 31
    • 16
    • 1
    单克隆
    标记
    • 25
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C3AR1 antibody is un-conjugated
    应用范围
    • 24
    • 22
    • 14
    • 13
    • 13
    • 10
    • 7
    • 6
    • 2
    Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody reacts with the receptor for C3a. It does not block binding of ligand to C3aR.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein G
    克隆位点
    17
    亚型
    IgG2b
    Top Product
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  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2 - 8 °C.
  • 抗原
    C3AR1 (Complement Component 3a Receptor 1 (C3AR1))
    Abstract
    C3AR1 产品
    别名
    C3AR antibody, C3a-R antibody, c3ar1 antibody, AZ3B antibody, HNFAG09 antibody, C3a anaphylatoxin chemotactic receptor antibody, complement C3a receptor 1 antibody, complement component 3a receptor 1 antibody, c3ar1 antibody, C3AR1 antibody, C3ar1 antibody
    背景
    In the course of complement activation the C3a receptor functions as the cell surface receptor for the anaphylatoxin C3a, the C-terminal 77 amino acid cleavage product of the alpha chain of C3, but not for C3a-desArg. All cellular responses to C3a are specifically mediated by interactions with the membrane bound C3a receptor, a seven transmembrane GTP-binding-protein-coupled receptor that belongs to the rhodopsin supergene family. The 54 kDa C3a receptor is widely distributed in, myeloid cells, peripheral tissues and the central nervous system. Expression of C3aR has been demonstrated on neutrophils, monocytes, eosinophils, astrocytes, neurons and glial cells and is increased in inflammatory conditions. No C3aR expression was detectable on lymphocytes and on tonsillar B cells even after stimulation.Synonyms: AZ3B, C3AR, C3AR1, C3R1, C3a anaphylatoxin chemotactic receptor, C3a-R, HNFAG09
    基因ID
    719
    NCBI登录号
    NP_004045
    UniProt
    Q16581
    途径
    Complement System
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