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Angiopoietin 2 抗体 (C-Term)

ANGPT2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1105366
发货至: 中国
  • 抗原 See all Angiopoietin 2 (ANGPT2) 抗体
    Angiopoietin 2 (ANGPT2)
    抗原表位
    • 15
    • 10
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 76
    • 37
    • 26
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 78
    • 10
    • 4
    • 1
    • 1
    • 1
    克隆类型
    • 69
    • 26
    多克隆
    标记
    • 49
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Angiopoietin 2 antibody is un-conjugated
    应用范围
    • 65
    • 32
    • 32
    • 13
    • 13
    • 12
    • 10
    • 10
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    序列
    Sequence is different from the related Mouse sequence by two amino acids.
    特异性
    This antibody detects Angiopoietin-2 near C-term. No cross reactivity with other proteins.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Synthetic peptide corresponding to a sequence mapping near the C-terminal of Human Angiopoietin-2
    亚型
    IgG
    Top Product
    Discover our top product ANGPT2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide, 5 mg BSA
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Angiopoietin 2 (ANGPT2)
    别名
    Angiopoietin-2 (ANGPT2 产品)
    别名
    AGPT2 antibody, ANG2 antibody, Agpt2 antibody, Ang-2 antibody, Ang2 antibody, ang2 antibody, angpt2 antibody, ANGIOPOIETIN-2 antibody, ANG-2 antibody, ANGPT2 antibody, Angrp antibody, Rnase5b antibody, ANG3 antibody, C11orf2 antibody, C11orf3 antibody, FFR antibody, angiopoietin 2 antibody, angiopoietin 2b antibody, angiogenin, ribonuclease A family, member 2 antibody, VPS51, GARP complex subunit antibody, ANGPT2 antibody, Angpt2 antibody, angpt2b antibody, Ang2 antibody, VPS51 antibody
    背景
    Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium, by regulating tyrosine phosphorylation of the membrane receptor Tie 2. Angiopoietin 2 is only 60 % homologous with Angiopoietin 1. Angiopoietin-2 is a naturally occurring antagonist of angiopoietin-1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation. Angiopoietin 1 binding to Tie 2 causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.Synonyms: ANG-2, ANG2, ANGPT2
    基因ID
    11601
    NCBI登录号
    NP_031452
    UniProt
    O35608
    途径
    RTK signaling
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