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POMC 抗体

POMC 适用: 人 IHC (p), EIA 宿主: 小鼠 Monoclonal 57 unconjugated
产品编号 ABIN1105257
发货至: 中国
  • 抗原 See all POMC 抗体
    POMC (Proopiomelanocortin (POMC))
    适用
    • 70
    • 42
    • 40
    • 2
    • 2
    • 1
    • 1
    宿主
    • 52
    • 37
    • 2
    • 1
    小鼠
    克隆类型
    • 53
    • 39
    单克隆
    标记
    • 64
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    • 2
    • 2
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    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
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    This POMC antibody is un-conjugated
    应用范围
    • 35
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    • 22
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    • 8
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Specific for Synacthen (1-24 ACTH). Reacts with ACTH (a.a. 1-17) and does not cross-react with CLIP (ACTH 17-39). It cross-reacts with Rat N-terminal ACTH.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Purified
    免疫原
    Keyhole Limpet Haemocyanin conjugated Human ACTH (1-17)
    克隆位点
    57
    亚型
    IgG1
    Top Product
    Discover our top product POMC Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) -20 °C for longer.
  • 抗原
    POMC (Proopiomelanocortin (POMC))
    别名
    POMC (POMC 产品)
    别名
    MSH antibody, ACTH antibody, pomc antibody, SI:bZ36D5.1 antibody, SI:bZ36D5.4 antibody, si:bz36d5.2 antibody, BE antibody, Beta-LPH antibody, Clip antibody, Gamma-LPH antibody, Npp antibody, Pomc-1 antibody, Pomc1 antibody, alpha-MSH antibody, alphaMSH antibody, beta-MSH antibody, gamma-MSH antibody, CLIP antibody, LPH antibody, NPP antibody, POC antibody, Pomc2 antibody, proopiomelanocortin a antibody, pro-opiomelanocortin-alpha antibody, proopiomelanocortin antibody, pomca antibody, Pomc antibody, POMC antibody
    背景
    ACTH (Synacthen) which, as a synthetic analogue of naturally-occurring Adrenocorticotropic Hormone, can be used to measure adrenal reserve and for the diagnosis of adrenal insufficiency by acute adrenocortical stimulation. ACTH, released from the anterior pituitary gland in response to corticotropin-releasing hormone from the hypothalamus, acts on the adrenal cortex to stimulate the production of corticosteroids such as cortisol, involved in the response to stress. Studies have shown that the administration of 1-24 ACTH increases blood pressure, believed to be attributed to an increase in ACTH-stimulated cortisol secretion, in association with increased cardiac output.Synonyms: Adrenocorticotropic hormone, Corticotropin, POMC
    基因ID
    5443
    NCBI登录号
    NP_000930
    UniProt
    P01189
    途径
    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour
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