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- 抗原 See all ACD 抗体
- ACD (Adrenocortical Dysplasia Homolog (ACD))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACD antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- KNRPPFPRTG ATRGAQEPCS VWEPPKRHRD GSAFQYEYEP PCTSLCARVQ
- 交叉反应 （详细）
- Species reactivity (expected):Bovine, Dog, Horse, Guinea PigSpecies reactivity (tested):Human
- 纯化方法
- Purified using peptide immunoaffinity column
- 免疫原
- Synthetic peptide directed towards the middle region of human ACD
- Top Product
- Discover our top product ACD Primary Antibody
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anti-Adrenocortical Dysplasia Homolog (ACD) (AA 1-544) antibody
ACD 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8-1B6 unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) antibodyACD 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2B1 unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 21-175) antibodyACD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 1-544) antibodyACD 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 1-544) antibodyACD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 328-497) antibodyACD 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) antibodyACD 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 467-516) antibodyACD 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 398-447) antibodyACD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenocortical Dysplasia Homolog (ACD) (AA 147-342) antibodyACD 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 溶解方式
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- 抗原
- ACD (Adrenocortical Dysplasia Homolog (ACD))
- 别名
- ACD (ACD 产品)
- 别名
- PIP1 antibody, PTOP antibody, TINT1 antibody, TPP1 antibody, ACD antibody, ACD, shelterin complex subunit and telomerase recruitment factor antibody, adrenocortical dysplasia antibody, ACD antibody, Acd antibody
- 背景
- Acd is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.Acd promotes binding of POT1 to single-stranded telomeric DNA.Acd modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomer elongation by increasing telomerase processivity.Acd plays a role in shelterin complex assembly. Acd may play an essential role in organogenesis of the developing embryo.Synonyms: Adrenocortical dysplasia protein homolog, PIP1, PTOP, TINT1, TPP1
- 基因ID
- 65057
- NCBI登录号
- NP_001075955
- 途径
- Telomere Maintenance
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