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ACD 产品

(Adrenocortical Dysplasia Homolog (ACD))

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This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008].

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Featured ACD Categories

ACD 抗体

High quality antibodies with extensive validation data.

ACD ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ACD 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ACD 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP, IF, IHC (p)
Validations
  • (2)
  • (5)
Cat. No. ABIN566298
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (6)
Cat. No. ABIN1496406
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7444562
Quantity 100 μL
Datasheet Datasheet

Recommended ACD ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN510363
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN778071
Quantity 96 tests
Datasheet Datasheet
Reactivity Rabbit
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN774172
Quantity 96 tests
Datasheet Datasheet

Recommended ACD 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305635
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3135189
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088119
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ACD Products

Frank, Tran, Qu, Stohr, Segal, Xu: "The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres." in: PLoS genetics, Vol. 11, Issue 7, pp. e1005410, (2015) (PubMed).

Abreu, Aritonovska, Reichenbach, Cristofari, Culp, Terns, Lingner, Terns: "TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo." in: Molecular and cellular biology, Vol. 30, Issue 12, pp. 2971-82, (2010) (PubMed).

Synonyms and alternative names related to ACD

ACD, shelterin complex subunit and telomerase recruitment factor (ACD), ACD, shelterin complex subunit and telomerase recruitment factor (Acd), adrenocortical dysplasia (Acd), ACD, PIP1, PTOP, TINT1, TPP1

Protein level used designations for ACD

  • POT1 and TIN2 organizing protein
  • POT1 and TIN2-interacting protein
  • TIN2 interacting protein 1
  • adrenocortical dysplasia protein homolog
  • adrenocortical dysplasia homolog (mouse)
  • adrenocortical dysplasia protein
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