CEACAM1/5 抗体
CEACAM1/5
适用: 人
FACS, WB, ELISA, cELISA, IHC (fro)
宿主: 小鼠
Monoclonal
4-3-17
unconjugated
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- 抗原 See all CEACAM1/5 products
- CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CEACAM1/5 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Cell-ELISA (cELISA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Anti-human CEACAM1, 5 (BGP, CEA, CD66a,e)
- 纯化方法
- Protein G
- 免疫原
- immunisation with extracted protein of CEACAM5
- 克隆位点
- 4-3-17
- 亚型
- IgG1
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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5) (N-Term) antibody
CEACAM1/5 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 Western blot: 4 µg/mL
Immunohistology: 1-2 µg/10^6 cells (on cryosections)
For each application a titration should be performed to determine the optimal concentration. - 说明
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Synonyms: CD66ae, BGP, CEA
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C
- 储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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- 抗原
- CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))
- 别名
- CEACAM1,5 (CEACAM1/5 产品)
- 别名
- CD66e antibody, CEA antibody, carcinoembryonic antigen related cell adhesion molecule 5 antibody, CEACAM5 antibody
- 背景
- Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
- UniProt
- P06731, P13688
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