CEACAM1/5 抗体 (CF®488A)
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- 抗原 See all CEACAM1/5 products
- CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CEACAM1/5 antibody is conjugated to CF®488A
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)
- 特异性
- This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
- 交叉反应 （详细）
- Human,
- 纯化方法
- Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules.
- 免疫原
- Recombinant full-length human CEA protein
- 克隆位点
- C66-1009
- 亚型
- IgG2a
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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5) (N-Term) antibody
CEACAM1/5 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5) antibodyCEACAM1/5 适用: 人 WB, FACS, ELISA, cELISA, IHC (fro) 宿主: 小鼠 Monoclonal 4-3-17 unconjugated
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- 应用备注
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Positive Control: MCF7 or 293T cells. Colon carcinoma.
Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 100 μg/mL
- 缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- 有效期
- 24 months
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- 抗原
- CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))
- 别名
- CEACAM1 & CEACAM5 (CEACAM1/5 产品)
- 别名
- CD66e antibody, CEA antibody, carcinoembryonic antigen related cell adhesion molecule 5 antibody, CEACAM5 antibody
- 背景
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Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1),Carcinoembryonic Antigen (CEA) / CD66
Cellular localisation: Cytoplasmic and luminal surface - 分子量
- 80-200kDa
- 基因ID
- 1048, 634, 709196
- UniProt
- P06731
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