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- 抗原 See all RC3H1 抗体
- RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This RC3H1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- At least three isoforms of RC3H1 are known to exist, this antibody will detect all three isoforms.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal RC3H1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RC3H1.
- 亚型
- IgG
- Top Product
- Discover our top product RC3H1 Primary Antibody
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anti-Ring Finger and CCCH-Type Domains 1 (RC3H1) (AA 1040-1090) antibody
RC3H1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger and CCCH-Type Domains 1 (RC3H1) (AA 834-1133) antibodyRC3H1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- RC3H1 antibody can be used for detection of RC3H1 by Western blot at 1 - 2 μg/mL.
- 说明
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(CT) Ring finger and CCCH-type domains 1
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C/-20 °C
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- 抗原
- RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))
- 别名
- RC3H1 (RC3H1 产品)
- 别名
- RNF198 antibody, ROQUIN antibody, RC3H1 antibody, si:dkey-192m14.4 antibody, 5730557L09Rik antibody, Gm551 antibody, N28103 antibody, mKIAA2025 antibody, RGD1563512 antibody, rc3h1 antibody, ring finger and CCCH-type domains 1 antibody, ring finger and CCCH-type domains 1a antibody, ring finger and CCCH-type zinc finger domains 1 antibody, RING CCCH (C3H) domains 1 antibody, ring finger and CCCH-type domains 1 L homeolog antibody, RC3H1 antibody, rc3h1a antibody, Rc3h1 antibody, rc3h1.L antibody
- 背景
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The ring finger protein RC3H1, also known as Roquin, is a highly conserved member of the RING type ubiquitin ligase protein family whose M199R mutation leads to the excessive production of follicular helper T cells and germinal centers in the sanroque strain of mice, a strain with excessive IL-21 production and high titers of autoantibodies. The complete loss of RC3H1 induces early death and immune deregulation but not autoimmunity in RC3H1-null mice, suggesting that the mutant RC3H1 is more disruptive to the immune system than its complete loss.
Synonyms: Ring finger and CCCH-type domains 1, ring finger protein 198, RNF198, roquin - 分子量
- 125 kDa
- 基因ID
- 149041
- NCBI登录号
- NP_742068
- 途径
- Ribonucleoprotein Complex Subunit Organization, Activated T Cell Proliferation
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