RC3H1 抗体 (C-Term)
RC3H1
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all RC3H1 抗体
- RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))
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抗原表位
- AA 1040-1090, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RC3H1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- At least three isoforms of RC3H1 are known to exist, this antibody will detect all three isoforms.
- 纯化方法
- RC3H1 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Rabbit polyclonal RC3H1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RC3H1. The immunogen is located within amino acids 1040 - 1090 of RC3H1.
- 亚型
- IgG
- Top Product
- Discover our top product RC3H1 Primary Antibody
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anti-Ring Finger and CCCH-Type Domains 1 (RC3H1) (AA 1040-1090) antibody
RC3H1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger and CCCH-Type Domains 1 (RC3H1) (AA 834-1133) antibodyRC3H1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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RC3H1 antibody can be used for detection of RC3H1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- RC3H1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- RC3H1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- RC3H1 (Ring Finger and CCCH-Type Domains 1 (RC3H1))
- 别名
- RC3H1 (RC3H1 产品)
- 背景
- RC3H1 Antibody: The ring finger protein RC3H1, also known as Roquin, is a highly conserved member of the RING type ubiquitin ligase protein family whose M199R mutation leads to the excessive production of follicular helper T cells and germinal centers in the sanroque strain of mice, a strain with excessive IL-21 production and high titers of autoantibodies. The complete loss of RC3H1 induces early death and immune deregulation but not autoimmunity in RC3H1-null mice, suggesting that the mutant RC3H1 is more disruptive to the immune system than its complete loss.
- 分子量
- 125 kDa
- 基因ID
- 149041
- NCBI登录号
- NP_742068
- UniProt
- Q5TC82
- 途径
- Ribonucleoprotein Complex Subunit Organization, Activated T Cell Proliferation
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