Prostaglandin D2 Receptor 2 (PTGDR2) 抗体
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- 抗原 See all Prostaglandin D2 Receptor 2 (PTGDR2) 抗体
- Prostaglandin D2 Receptor 2 (PTGDR2)
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal PTGDR2 antibody was raised against a 19 amino acid peptide near the center of human PTGDR2.
- 亚型
- IgG
- Top Product
- Discover our top product PTGDR2 Primary Antibody
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- 应用备注
- PTGDR2 antibody can be used for detection of PTGDR2 by Western blot at 0.5 - 1 μg/mL.
- 说明
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(IN) Prostaglandin D2 receptor 2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C
- 储存方法
- PTGDR2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
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- 抗原
- Prostaglandin D2 Receptor 2 (PTGDR2)
- 别名
- PTGDR2 (PTGDR2 产品)
- 别名
- CD294 antibody, CRTH2 antibody, DL1R antibody, DP2 antibody, GPR44 antibody, Crth2 antibody, Grp45 antibody, Ptgdr2 antibody, Gpr44 antibody, prostaglandin D2 receptor 2 antibody, PTGDR2 antibody, Ptgdr2 antibody
- 背景
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The prostaglandin D2 receptor 2 (PTGDR2), also known as CRTH2, is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, PTGDR2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the PTGDR2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that PTGDR2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.
Synonyms: Prostaglandin D2 receptor 2, chemoattractant receptor-homologous molecule expressed on Th2 cells, CRTH2, G protein-coupled receptor 44, GPR44, CD294, DL1R, DP2 - 分子量
- 43 kDa (calculated)
- 基因ID
- 11251
- NCBI登录号
- NP_004769
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
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