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Prostaglandin D2 Receptor 2 (PTGDR2) 抗体

PTGDR2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN1077429
发货至: 中国
  • 抗原 See all Prostaglandin D2 Receptor 2 (PTGDR2) 抗体
    Prostaglandin D2 Receptor 2 (PTGDR2)
    适用
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    人, 小鼠
    宿主
    • 52
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    克隆类型
    • 53
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    单克隆
    标记
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    非结合性
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Rabbit polyclonal PTGDR2 antibody was raised against a 19 amino acid peptide near the center of human PTGDR2.
    亚型
    IgG
    Top Product
    Discover our top product PTGDR2 Primary Antibody
  • 应用备注
    PTGDR2 antibody can be used for detection of PTGDR2 by Western blot at 0.5 - 1 μg/mL.
    说明

    (IN) Prostaglandin D2 receptor 2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    储存条件
    4 °C
    储存方法
    PTGDR2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
    有效期
    12 months
  • 抗原
    Prostaglandin D2 Receptor 2 (PTGDR2)
    别名
    PTGDR2 (PTGDR2 产品)
    别名
    CD294 antibody, CRTH2 antibody, DL1R antibody, DP2 antibody, GPR44 antibody, Crth2 antibody, Grp45 antibody, Ptgdr2 antibody, Gpr44 antibody, prostaglandin D2 receptor 2 antibody, PTGDR2 antibody, Ptgdr2 antibody
    背景
    The prostaglandin D2 receptor 2 (PTGDR2), also known as CRTH2, is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, PTGDR2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the PTGDR2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that PTGDR2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.
    Synonyms: Prostaglandin D2 receptor 2, chemoattractant receptor-homologous molecule expressed on Th2 cells, CRTH2, G protein-coupled receptor 44, GPR44, CD294, DL1R, DP2
    分子量
    43 kDa (calculated)
    基因ID
    11251
    NCBI登录号
    NP_004769
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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