TYK2 抗体 (N-Term)
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- 抗原 See all TYK2 抗体
- TYK2 (Tyrosine Kinase 2 (TYK2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TYK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- At least three isoforms of TYK2 are known to exist, this antibody only detects the two longest isoforms.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal TYK2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TYK2.
- 亚型
- IgG
- Top Product
- Discover our top product TYK2 Primary Antibody
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- 应用备注
- TYK2 antibody can be used for detection of TYK2 by Western blot at 1 - 2 μg/mL.
- 说明
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(NT) Tyrosine kinase 2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C
- 储存方法
- TYK2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
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- 抗原
- TYK2 (Tyrosine Kinase 2 (TYK2))
- 别名
- TYK2 (TYK2 产品)
- 别名
- JTK1 antibody, tyrosine kinase 2 antibody, TYK2 antibody, Tyk2 antibody
- 背景
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TYK2 is a member of the Janus kinases (JAKs) protein families. TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits and is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Synonyms: Tyrosine kinase 2, non-receptor tyrosine kinase 2 - 分子量
- 131 kDa (calculated)
- 基因ID
- 7297
- NCBI登录号
- NP_003322
- 途径
- JAK/STAT Signaling, Hepatitis C
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