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- 抗原 See all CRB2 抗体
- CRB2 (Crumbs Homolog 2 (CRB2))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CRB2 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 特异性
- At least three isoforms of CRB2 are known to exist, this antibody will detect all three. CRB2 antibody is predicted to not cross-react with other members of the CRB family.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Rabbit polyclonal CRB2 antibody was raised against a 17 amino acid peptide near the center of human CRB2.
- 亚型
- IgG
- Top Product
- Discover our top product CRB2 Primary Antibody
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anti-Crumbs Homolog 2 (CRB2) (AA 1258-1285) antibody
CRB2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB27068 unconjugated
anti-Crumbs Homolog 2 (CRB2) (AA 701-800) antibodyCRB2 适用: 小鼠, 大鼠 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Crumbs Homolog 2 (CRB2) (AA 253-483) antibodyCRB2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- CRB2 antibody can be used for detection of CRB2 by Western blot at 1 - 2 μg/mL.
- 说明
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(IN) Crumbs homolog 2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C
- 储存方法
- CRB2 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
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- 抗原
- CRB2 (Crumbs Homolog 2 (CRB2))
- 别名
- CRB2 (CRB2 产品)
- 别名
- 5930402A21 antibody, BC043114 antibody, RGD1309368 antibody, crb2 antibody, crumbs family member 2 antibody, crumbs 2, cell polarity complex component antibody, crumbs family member 2a antibody, Crb2 antibody, CRB2 antibody, crb2a antibody
- 背景
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CRB2 (Crumbs homolog 2), like its homologs CRB1 and CRB3, is similar to the Drosophila crumbs protein and is expressed in retina, brain and kidney. Along with other proteins, the Crumbs proteins form a complex that help set up cell polarity in developing neuroepithelial cells. At the onset of neural specification, embryonic stem cells (ESCs) upregulate CRB2, which then localizes apically in neural rosettes. Gain- and loss-of-function studies of CRB2 have shown that CRB2 is essential for the stabilization of other polarity proteins. Unlike CRB1, mutations in CRB2 do not appear to play a role in retinitis pigmentosa or in Leber congenital amaurosis.
Synonyms: Crumbs homolog 2, crumbs 2, crumbs-like protein 2 - 分子量
- 141 kDa (calculated)
- 基因ID
- 286204
- NCBI登录号
- NP_775960
- 途径
- Notch Signaling
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