ATG14 抗体
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- 抗原 See all ATG14 抗体
- ATG14 (ATG14 Autophagy Related 14 (ATG14))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATG14 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 特异性
- At least three isoforms of ATG14 are known to exist, this antibody will detect all three isoforms
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- ATG14 antibody was raised against an 18 amino acid synthetic peptide near the center of human ATG14.
- 亚型
- IgG
- Top Product
- Discover our top product ATG14 Primary Antibody
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- 应用备注
- ATG14 antibody can be used for detection of ATG14 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
- 说明
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(IN) Autophagy-related 14
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 储存条件
- 4 °C
- 储存方法
- ATG14 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
- 有效期
- 12 months
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- 抗原
- ATG14 (ATG14 Autophagy Related 14 (ATG14))
- 别名
- ATG14 (ATG14 产品)
- 别名
- ATG14L antibody, BARKOR antibody, KIAA0831 antibody, 4832427M01 antibody, Atg14L antibody, D14Ertd114e antibody, D14Ertd436e antibody, RGD1304610 antibody, autophagy related 14 antibody, ATG14 antibody, Atg14 antibody
- 背景
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Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation.
Synonyms: Autophagy-related 14, ATG14L, beclin1-associated autophagy-related key regulator, beclin 1-interacting protein, BARKOR - 分子量
- 54 kDa
- 基因ID
- 22863
- NCBI登录号
- NP_055739
- 途径
- Autophagy
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