我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

RAGE 抗体 (AA 23-342) (HRP)

Name: RAGE 抗体 (AA 23-342) (HRP)
SKU: ABIN1045203
Availability: OutOfStock

AGER 适用: 人 ELISA 宿主: 兔 Polyclonal HRP

产品编号 ABIN1045203

发货至: 中国

Datasheet as PDF

抗原 See all RAGE (AGER) 抗体

RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
抗原表位
19

16

16

11

9

9

8

7

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 23-342
适用
137

79

61

7

5

4

3

3

2

2

1
人
宿主
130

10

4

2

1
兔
Compatible Secondaries
克隆类型
125

21

1
多克隆
标记
65

11

10

9

8

5

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This RAGE antibody is conjugated to HRP
应用范围
119

63

48

32

27

26

21

11

8

7

7

3

2

1

1

1
ELISA

交叉反应

人

纯化方法

>95%, Protein G purified

免疫原

Recombinant Human Advanced glycosylation end product-specific receptor protein (23-342AA)

亚型

IgG

Top Product

Discover our top product AGER Primary Antibody
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 180-402) antibody
AGER 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 1-404) antibody
AGER 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 151-250) antibody
AGER 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IP, IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 91-274) antibody
AGER 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 23-404) antibody
AGER 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C1 unconjugated

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 91-120), (N-Term) antibody
AGER 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 76-104) antibody
AGER 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) antibody
AGER 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) antibody (Cy3)
AGER 适用: 人, Cow WB, IHC, ELISA, IHC (p), ICC 宿主: 小鼠 Monoclonal DD-A11 Cy3

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (N-Term) antibody
AGER 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, Pig WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Liquid

缓冲液

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

注意事项

Avoid freeze and thaw cycles.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

别名

AGER (AGER 产品)

别名

RAGE antibody, AGER antibody, advanced glycosylation end-product specific receptor antibody, advanced glycosylation end product-specific receptor antibody, MAPK/MAK/MRK overlapping kinase antibody, AGER antibody, Ager antibody, LOC719012 antibody

背景

Background: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling By similarity. Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space.
Aliases: Advanced glycosylation end product-specific receptor antibody, Ager antibody, DAMA 358M23.4 antibody, MGC2235 antibody, MGC22357 antibody, RAGE_HUMAN antibody, Receptor for advanced glycation end products antibody, Receptor for advanced glycosylation end products antibody

UniProt

Q15109

途径

Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins