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STING/TMEM173 抗体

(Transmembrane Protein 173 (TMEM173))
Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double- stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti- viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
STING/TMEM173 抗体  (AA 159-373) STING/TMEM173 抗体  (AA 159-373) STING/TMEM173 抗体 (AA 159-373) (ABIN7439447)

TMEM173 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

STING/TMEM173 抗体 STING/TMEM173 抗体 STING/TMEM173 抗体 (ABIN1501428)

TMEM173 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4H8 unconjugated

STING/TMEM173 抗体  (AA 170-379) STING/TMEM173 抗体  (AA 170-379) STING/TMEM173 抗体 (AA 170-379) (ABIN1683049)

TMEM173 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated

STING/TMEM173 抗体 by 适用

Find STING/TMEM173 抗体 for a variety of species such as anti-Human STING/TMEM173, anti-Rat STING/TMEM173, anti-Mouse STING/TMEM173. The species listed below are among those available. Click on a link to go to the corresponding products.

STING/TMEM173 抗体 by 应用范围

Find STING/TMEM173 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find STING/TMEM173 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

STING/TMEM173 抗体 by 抗原表位

Find STING/TMEM173 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

STING/TMEM173 抗体 by 克隆形成能力

Find available monoclonal or polyclonal STING/TMEM173 抗体. Click on a link to go to the corresponding products.

STING/TMEM173 抗体 by 克隆

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STING/TMEM173 抗体 by 标记

Find STING/TMEM173 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular STING/TMEM173 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7439447
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (9)
Cat. No. ABIN1501428
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, IF
Validations
  • (8)
Cat. No. ABIN1683049
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (1)
Cat. No. ABIN3043423
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7270958
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (5)
Cat. No. ABIN3029261
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7170794
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6265612
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN1501423
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p)
Validations
  • (2)
Cat. No. ABIN3187979
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5014445
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN653764
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Pig
Application WB
Validations
  • (3)
  • (2)
Cat. No. ABIN2783202
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p), EIA
Validations
  • (3)
Cat. No. ABIN955253
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Rat
Application ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN1386059
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our STING/TMEM173 抗体

Zhang, Wei, Cui, Hong, Liu, Wang, Li, Liu, Yu, Cai, Wang, Zhu, Meng, Chen, Wang: "The deubiquitinase CYLD is a specific checkpoint of the STING antiviral signaling pathway." in: PLoS pathogens, Vol. 14, Issue 11, pp. e1007435, (2019) (PubMed).

Gentili, Lahaye, Nadalin, Nader, Puig Lombardi, Herve, De Silva, Rookhuizen, Zueva, Goudot, Maurin, Bochnakian, Amigorena, Piel, Fachinetti, Londoño-Vallejo, Manel: "The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus." in: Cell reports, Vol. 26, Issue 9, pp. 2377-2393.e13, (2019) (PubMed).

Yang, Lee, Kong, Kim, Kim, Chang, Kim, Kim, Chon, Kim: "STING activation reprograms tumor vasculatures and synergizes with VEGFR2 blockade." in: The Journal of clinical investigation, Vol. 130, pp. 4350-4364, (2019) (PubMed).

Gaston, Cheradame, Yvonnet, Deas, Poupon, Judde, Cairo, Goffin: "Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents." in: Oncotarget, Vol. 7, Issue 47, pp. 77205-77224, (2018) (PubMed).

Choi, Park, Kang, Lee, Lee, Ra, Lee, Lee, Park: "Human cytomegalovirus-encoded US9 targets MAVS and STING signaling to evade type I interferon immune responses." in: Nature communications, Vol. 9, Issue 1, pp. 125, (2018) (PubMed).

Albertini, Lo Cigno, Calati, De Andrea, Borgogna, DellOste, Landolfo, Gariglio: "HPV18 Persistence Impairs Basal and DNA Ligand-Mediated IFN-β and IFN-λ1 Production through Transcriptional Repression of Multiple Downstream Effectors of Pattern Recognition Receptor Signaling." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 6, pp. 2076-2089, (2018) (PubMed).

Ghosh, Roy, Franco: "PARP1 depletion induces RIG-I-dependent signaling in human cancer cells." in: PLoS ONE, Vol. 13, Issue 3, pp. e0194611, (2018) (PubMed).

Yang, Wang, Ketkar, Ma, Yang, Cui, Geng, Mordue, Fujimoto, Cheng, You, Lin, Fikrig, Wang: "UBXN3B positively regulates STING-mediated antiviral immune responses." in: Nature communications, Vol. 9, Issue 1, pp. 2329, (2018) (PubMed).

Bhattacharya, Srinivasan, Abdisalaam, Su, Raj, Dozmorov, Mishra, Wakeland, Ghose, Mukherjee, Asaithamby: "RAD51 interconnects between DNA replication, DNA repair and immunity." in: Nucleic acids research, Vol. 45, Issue 8, pp. 4590-4605, (2017) (PubMed).

Chen, Shen, Hsia, Tiang, Sung, Chen: "Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway." in: Nature structural & molecular biology, Vol. 24, Issue 12, pp. 1124-1131, (2017) (PubMed).

Aliases for STING/TMEM173 抗体

transmembrane protein 173 (TMEM173) 抗体
transmembrane protein 173 (Tmem173) 抗体
2610307O08Rik 抗体
ERIS 抗体
MITA 抗体
Mita 抗体
MPYS 抗体
NET23 抗体
RGD1562552 抗体
STING 抗体
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