ACE2 蛋白
(Angiotensin I Converting Enzyme 2 (ACE2))
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ACE2 Protein (His tag,AVI tag,Biotin) | 人 | HEK-293 Cells |
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| ACE2 Protein (AA 18-740) (Biotin,His-Avi Tag) | 人 | HEK-293 Cells |
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| ACE2 Protein (His tag) | Paguma larvata | HEK-293 Cells |
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| ACE2 Protein (AA 18-739) (His-Avi Tag) | Cynomolgus | HEK-293 Cells |
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| ACE2 Protein (AA 18-740) (hFc-Avi Tag,Biotin) | 人 | HEK-293 Cells |
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| ACE2 Protein (AA 18-740) (His-Avi Tag) | 人 | HEK-293 Cells |
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| ACE2 Protein (AA 18-740) (His tag) | 人 | HEK-293 Cells |
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| ACE2 Protein (AA 18-740) (mFc Tag) | 人 | HEK-293 Cells |
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| ACE2 Protein (AA 18-740) (Fc Tag) | 人 | HEK-293 Cells |
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| ACE2 Protein (AA 18-739) (Biotin,His-Avi Tag) | Cynomolgus | HEK-293 Cells |
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| ACE2 Protein (AA 18-740) (Fc Tag) | 人 | HEK-293 Cells |
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| ACE2 Protein (AA 18-739) (Fc Tag) | 猕猴 | HEK-293 Cells |
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| ACE2 Protein (AA 18-739) (His tag) | 猕猴 | HEK-293 Cells |
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| ACE2 Protein (AA 18-740) (His-Avi Tag) | 人 | HEK-293 Cells |
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| ACE2 Protein (AA 18-740) (His tag) | 大鼠 | Baculovirus infected Insect Cells |
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| ACE2 Protein (His tag) | 小鼠 | HEK-293 Cells |
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| ACE2 Protein (AA 18-740) (His tag) | 人 | 人细胞 |
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| ACE2 Protein (His-Fc tag) | 小鼠 | HEK-293 Cells |
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| ACE2 Protein (His tag) | 大鼠 | HEK-293 Cells |
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| ACE2 Protein (Fc Tag,AVI tag,Biotin) | 人 | HEK-293 Cells |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- BLI (Bio-Layer Interferometry: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SPR (Surface Plasmon Resonance: 有验证图片)
- Func (Functional Studies: 所列应用)
1 reference - 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- BLI (Bio-Layer Interferometry: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SPR (Surface Plasmon Resonance: 有验证图片)
- 宿主
- Paguma larvata
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- ScA (Screening Assay: 所列应用)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- ScA (Screening Assay: 所列应用)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- ScA (Screening Assay: 所列应用)
- AM (Affinity Measurement: 所列应用)
- ADA (Antibody Drug Assay: 所列应用)
- IA (Immunoassay: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: 有验证图片)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
- 宿主
- Cynomolgus
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- Func (Functional Studies: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % by SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 宿主
- 猕猴
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- ELISA (ELISA: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 宿主
- 猕猴
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- Func (Functional Studies: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 大鼠
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- Func (Functional Studies: 所列应用)
- 宿主
- 人
- 宿主
- 人细胞
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- 宿主
- 大鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- ELISA (ELISA: 有验证图片)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- >95 % as determined by SDS-PAGE.
Latest Publications for our ACE2 蛋白
: "SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination." in: Advanced materials (Deerfield Beach, Fla.), Vol. 32, Issue 50, pp. e2005637, (2021) (PubMed).
: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." in: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).
: "Dromedary camels as a natural source of neutralizing nanobodies against SARS-CoV-2." in: JCI insight, (2021) (PubMed).
: "SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity." in: Nature communications, Vol. 12, Issue 1, pp. 848, (2021) (PubMed).
: "Chicken Egg Yolk Antibodies (IgYs) block the binding of multiple SARS-CoV-2 spike protein variants to human ACE2." in: International immunopharmacology, Vol. 90, pp. 107172, (2021) (PubMed).
: "Neutralizing antibodies targeting the SARS-CoV-2 receptor binding domain isolated from a naïve human antibody library." in: Protein science : a publication of the Protein Society, Vol. 30, Issue 4, pp. 716-727, (2021) (PubMed).
: "A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency." in: Antiviral research, Vol. 194, pp. 105147, (2021) (PubMed).
: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)
: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).
: "Development of cell-based pseudovirus entry assay to identify potential viral entry inhibitors and neutralizing antibodies against SARS-CoV-2." in: Genes & diseases, (2020) (PubMed).
: "SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus." in: Communications biology, Vol. 4, Issue 1, pp. 129, (2021) (PubMed).
: "Dromedary camels as a natural source of neutralizing nanobodies against SARS-CoV-2." in: JCI insight, (2021) (PubMed).
: "SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity." in: Nature communications, Vol. 12, Issue 1, pp. 848, (2021) (PubMed).
: "Chicken Egg Yolk Antibodies (IgYs) block the binding of multiple SARS-CoV-2 spike protein variants to human ACE2." in: International immunopharmacology, Vol. 90, pp. 107172, (2021) (PubMed).
: "Neutralizing antibodies targeting the SARS-CoV-2 receptor binding domain isolated from a naïve human antibody library." in: Protein science : a publication of the Protein Society, Vol. 30, Issue 4, pp. 716-727, (2021) (PubMed).
: "A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency." in: Antiviral research, Vol. 194, pp. 105147, (2021) (PubMed).
: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)
: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).
: "Development of cell-based pseudovirus entry assay to identify potential viral entry inhibitors and neutralizing antibodies against SARS-CoV-2." in: Genes & diseases, (2020) (PubMed).
Aliases for ACE2 蛋白
angiotensin I converting enzyme (ACE) 蛋白angiotensin I converting enzyme 2 (ACE2) 蛋白
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (Ace2) 蛋白
angiotensin I converting enzyme 2 (Ace2) 蛋白
angiotensin I converting enzyme 2 (ace2) 蛋白
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2) 蛋白
2010305L05Rik 蛋白
ACE1 蛋白
ACEH 蛋白
CD143 蛋白
DCP 蛋白
DCP1 蛋白
ICH 蛋白
MVCD3 蛋白
zgc:92514 蛋白
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