ACLY 蛋白
(ATP Citrate Lyase (ACLY))
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ACLY Protein (AA 4-265) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| ACLY Protein (AA 2-180) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| ACLY Protein (AA 1-1101) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| ACLY Protein (AA 1-1091) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| ACLY Protein (His tag) | 人 | Baculovirus infected Insect Cells |
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| ACLY Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) | 人 | HEK-293 Cells |
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| ACLY Protein (partial) (His-SUMO Tag) | 人 | 大肠杆菌（E. Coli） |
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| ACLY Protein (AA 495-1092) (His tag) | 人 | Bacteria |
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| ACLY Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: 有验证图片)
- AbP (Antibody Production: 所列应用)
- STD (Standard: 所列应用)
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Protein
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- SDS (SDS-PAGE: 所列应用)
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
Latest Publications for our ACLY 蛋白
: "mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer." in: Oncotarget, Vol. 7, Issue 18, pp. 25224-40, (2018) (PubMed).
Aliases for ACLY 蛋白
ATP citrate lyase (ACLY) 蛋白ATP citrate lyase S homeolog (acly.S) 蛋白
ATP-citrate synthase (LOC587157) 蛋白
ATP citrate lyase (acly) 蛋白
ATP citrate lyase (ATPCL) 蛋白
ATP-citrate synthase (LOC5564509) 蛋白
citrate synthase, mitochondrial (CpipJ_CPIJ010291) 蛋白
ATP-citrate synthase (Bm1_26245) 蛋白
atp-citrate synthase (ACL) 蛋白
ATP citrate lyase (Acly) 蛋白
ATP citrate lyase a (aclya) 蛋白
A730098H14Rik 蛋白
ACL 蛋白
ACLY 蛋白
acly 蛋白
anon-WO0140519.179 蛋白
ATPCL 蛋白
AW538652 蛋白
BcDNA:LD21334 蛋白
cb722 蛋白
CG8322 蛋白
CLATP 蛋白
Clatp 蛋白
dATPCL 蛋白
DDBDRAFT_0205389 蛋白
DDBDRAFT_0235360 蛋白
DDB_0205389 蛋白
DDB_0235360 蛋白
DmATPCL 蛋白
Dmel\\CG8322 蛋白
l(2)01466 蛋白
l(2)k09217 蛋白
n(2)k09217 蛋白
zgc:92008 蛋白
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