WWOX 抗体
(WW Domain Containing Oxidoreductase (WWOX))
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008].
recommended
recommended
WWOX 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
recommended
WWOX 抗体 by 适用
Find WWOX 抗体 for a variety of species such as anti-Human WWOX, anti-Mouse WWOX, anti-Rat WWOX. The species listed below are among those available. Click on a link to go to the corresponding products.
WWOX 抗体 by 抗体来源
Find WWOX 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
WWOX 抗体 by 克隆形成能力
Find available monoclonal or polyclonal WWOX 抗体. Click on a link to go to the corresponding products.
WWOX 抗体 by 克隆
Find WWOX 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
WWOX 抗体 by 标记
Find WWOX 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular WWOX 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF, IP
Validations
- (6)
Cat. No.
ABIN7175871
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (3)
Cat. No.
ABIN670551
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (5)
Cat. No.
ABIN5693294
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN5708495
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7138983
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7244447
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN526913
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6259234
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN7256280
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IF
Validations
- (1)
Cat. No.
ABIN7256278
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Cow, Guinea Pig, Horse, Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6747534
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IHC (p), ICC
Validations
- (1)
Cat. No.
ABIN1804276
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (1)
Cat. No.
ABIN6150273
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN1532116
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Chicken, Human, Mouse, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN7303028
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our WWOX 抗体
: "PGBD5 promotes site-specific oncogenic mutations in human tumors. ..." in: Nature genetics, Vol. 49, Issue 7, pp. 1005-1014, (2017) (PubMed).: "The ectopic expression of BRCA1 is associated with genesis, progression, and prognosis of breast cancer in young patients." in: Diagnostic pathology, Vol. 7, pp. 181, (2013) (PubMed).
: "WWOX gene restoration prevents lung cancer growth in vitro and in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 43, pp. 15611-6, (2005) (PubMed).
: "Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinoma." in: British journal of cancer, Vol. 91, Issue 4, pp. 753-9, (2004) (PubMed).
: "JNK1 physically interacts with WW domain-containing oxidoreductase (WOX1) and inhibits WOX1-mediated apoptosis." in: The Journal of biological chemistry, Vol. 278, Issue 11, pp. 9195-202, (2003) (PubMed).
: "WWOX, the FRA16D gene, behaves as a suppressor of tumor growth." in: Cancer research, Vol. 61, Issue 22, pp. 8068-73, (2001) (PubMed).
: "WWOX: a candidate tumor suppressor gene involved in multiple tumor types." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 20, pp. 11417-22, (2001) (PubMed).
: "WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer." in: Cancer research, Vol. 60, Issue 8, pp. 2140-5, (2000) (PubMed).
: "Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells." in: Human molecular genetics, Vol. 9, Issue 11, pp. 1651-63, (2000) (PubMed).
Aliases for WWOX 抗体
WW domain containing oxidoreductase (Wwox) 抗体WW domain-containing oxidoreductase (LOC411815) 抗体
WW domain containing oxidoreductase (WWOX) 抗体
WW domain-containing oxidoreductase (CpipJ_CPIJ004939) 抗体
WW domain-containing oxidoreductase (MCYG_01584) 抗体
WW domain-containing oxidoreductase (VDBG_05631) 抗体
WW domain-containing oxidoreductase (VDBG_01326) 抗体
WW domain-containing oxidoreductase (VDBG_06753) 抗体
WW domain-containing oxidoreductase (Tsp_03967) 抗体
WW domain-containing oxidoreductase (LOC100284583) 抗体
WW domain containing oxidoreductase (wwox) 抗体
WW domain-containing oxidoreductase (Wwox) 抗体
5330426P09Rik 抗体
9030416C10Rik 抗体
anon-EST:Posey177 抗体
CG7221 抗体
D16S432E 抗体
Dmel\\CG7221 抗体
DmWWOX 抗体
FOR 抗体
FRA16D 抗体
GB11795 抗体
HHCMA56 抗体
PRO0128 抗体
SDR41C1 抗体
WOX1 抗体
WWOX 抗体
zgc:55975 抗体
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