anti-Sphingomyelin Synthase 2 (SGMS2) 抗体

Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. 再加上,我们可以发Sphingomyelin Synthase 2 试剂盒 (6)Sphingomyelin Synthase 2 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SGMS2 166929 Q8NHU3
SGMS2 74442 Q9D4B1
SGMS2 310849 Q4JM44
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Showing 10 out of 66 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-SGMS2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 EIA, FACS, IHC (p), WB Flow Cytometric analysis of MCF-7 cells using SGMS2 Antibody (C-term) Cat.-No AP53890PU-N (Right histogram) compared to a negative control cell (Left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue stained with SGMS2 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SGMS2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 EIA, WB Western blot analysis of SGMS2 (arrow) using SGMS2 Antibody (C-term) Cat.-No AP53889PU-N. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SGMS2 gene. 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 IHC, IHC (p), WB Immunohistochemistry-Paraffin: Sphingomyelin Synthase 2 Antibody [NBP1-92436] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells. Western Blot: Sphingomyelin Synthase 2 Antibody [NBP1-92436] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 10至13个工作日
$494.38
详细
Bat 非结合性 WB 50 μg Log in to see 11至14个工作日
$551.83
详细
非结合性 FACS, IHC (p), WB SGMS2 Antibody (C-term) (ABIN653758) western blot analysis in MCF-7,CEM,Hela cell line lysates (35 µg/lane).This demonstrates the SGMS2 antibody detected the SGMS2 protein (arrow). SGMS2 Antibody (C-term) (ABIN653758) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10至11个工作日
$385.00
详细
非结合性 WB Western blot analysis of SGMS2 Antibody (C-term) (ABIN653696) in HepG2 cell line lysates (35 µg/lane). SGMS2 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of SGMS2 Antibody (C-term) (ABIN653696) in mouse spleen tissue lysates (35 µg/lane). SGMS2 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10至11个工作日
$385.00
详细
非结合性 WB Western Blot: Sphingomyelin Synthase 2 Antibody [NBP1-60005] - Titration: 0.2-1 ug/ml, Positive Control: 293T cell lysate. 100 μL Log in to see 8至11个工作日
$488.73
详细
小鼠 非结合性 RNAi, ELISA, WB Western blot analysis of MGC26963 over-expressed 293 cell line, cotransfected with MGC26963 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with MGC26963 monoclonal antibody (M08), clone 7D10. GAPDH ( 36.1 kDa ) used as specificity and loading control. Western Blot analysis of MGC26963 expression in transfected 293T cell line by MGC26963 monoclonal antibody (M08), clone 7D10.Lane 1: MGC26963 transfected lysate(42.3 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 11至12个工作日
$440.00
详细
非结合性 WB Western Blot: Sphingomyelin Synthase 2 Antibody [NBP1-60004] - Sphingomyelin Synthase 2 expression in mouse lung lysate using anti-Sphingomyelin Synthase 2 antibody. Image from verified customer review. Western Blot: Sphingomyelin Synthase 2 Antibody [NBP1-60004] - Titration: 0.2-1 ug/ml, Positive Control: Human heart. 100 μL Log in to see 8至11个工作日
$488.73
详细

引用最多的anti-Sphingomyelin Synthase 2 抗体

  1. Human Polyclonal Sphingomyelin Synthase 2 Primary Antibody for WB - ABIN4892660 : Ding, Li, Hailemariam, Mukherjee, Maxfield, Wu, Jiang: SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis. in Journal of lipid research 2008 (PubMed)

更多抗Sphingomyelin Synthase 2的相互作用对抗体

Human Sphingomyelin Synthase 2 (SGMS2) interaction partners

  1. SMS regulates the expression and function of drug transporters P-gp and MRP2.

  2. findings suggest that the C-terminal tails of SMSs are involved in homodimer formation, which is required for efficient transport from the ER.

  3. PPARdelta activation may be a potential risk of atherosclerosis through enhancing activity of SMS2

  4. F-actin polymerization in the region of HIV-1 membrane fusion was more prominent in Sms2-expressing cells than Sms-deficient cells.

  5. SMS1 and SMS2 are capable of regulating TGN-mediated protein trafficking and secretion

  6. Data indicate that the increased sphingomyelin mass was due to a rapid and highly specific activation of sphingomyelin synthases SMS1 and SMS2.

  7. direct morphological evidence for the pro-atherogenic capabilities of sphingomyelin synthase 2

  8. Data show that SMS2 acting as a bifunctional enzyme with both SM and CPE synthase activity.

  9. Data show that sphingomyelin synthases SMS1 and SMS2 are co-expressed in a variety of cell types and function as the key Golgi- and plasma membrane-associated SM synthases in human cervical carcinoma HeLa cells, respectively.

  10. Results indicate that both synthase (SMS)1 and 2 contribute to sphingomyelin (SM) de novo synthesis and control SM levels in the cells and on the cell membrane including plasma membrane.

  11. SMS2 is a key factor in control of sphingomyelin and diacylglycerol metabolism within the cell, and thus it influences apoptosis.

  12. SMS2 regulates subcellular pools of diacylglycerol-binding proteins in the Golgi apparatus.

  13. SMS2 (Sphingomyelin synthase 2) physiologically contributes to de novo Sphingomyelin biosynthesis and plasma membrane Sphingomyelin levels

  14. Both SMS1 and SMS2 contain two histidines and one aspartic acid which are conserved within the lipid phosphate phosphatase superfamily. Site-directed mutagenesis of these amino acids abolished SMS activity without altering cellular distribution.

  15. These results suggested that posttranslational palmitoylation is important for determination of the subcellular localization of SMS2.

  16. Sphingomyelin synthase 2 is one of the determinants for plasma and liver sphingomyelin levels in mice.

Sphingomyelin Synthase 2 (SGMS2) 抗原简介

蛋白简介

Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. Three transcript variants encoding the same protein have been found for this gene. There is evidence for more variants, but the full-length nature of their transcripts has not been determined.

Gene names and symbols associated with SGMS2

  • sphingomyelin synthase 2 (sgms2) 抗体
  • sphingomyelin synthase 2 (SGMS2) 抗体
  • sphingomyelin synthase 2 (Sgms2) 抗体
  • 4933405A16Rik 抗体
  • 5133401H06Rik 抗体
  • AI854299 抗体
  • RGD1305778 抗体
  • SMS2 抗体
  • spermatin 抗体

Protein level used designations for SGMS2

sphingomyelin synthase 2 , phosphatidylcholine:ceramide cholinephosphotransferase 2 , phosphatidylcholine:ceramide cholinephosphotransferase 2-like , SM synthase

GENE ID SPECIES
496853 Xenopus (Silurana) tropicalis
695947 Macaca mulatta
735414 Pan troglodytes
100072971 Equus caballus
100079264 Ornithorhynchus anatinus
100400486 Callithrix jacchus
100446194 Pongo abelii
100466473 Ailuropoda melanoleuca
100593842 Nomascus leucogenys
166929 Homo sapiens
556193 Danio rerio
422529 Gallus gallus
478505 Canis lupus familiaris
100518796 Sus scrofa
520954 Bos taurus
74442 Mus musculus
310849 Rattus norvegicus
100715504 Cavia porcellus
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