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SPEN 抗体

(Spen Homolog, Transcriptional Regulator (SPEN))
This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator\; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008].
SPEN 抗体 (Internal Region) (ABIN185595)

Recent SPEN 适用: 人 ELISA 宿主: 山羊 Polyclonal unconjugated

SPEN 抗体 (AA 1350-1400) (ABIN7451040)

SPEN 适用: 人 IP 宿主: 兔 Polyclonal unconjugated

SPEN 抗体 (AA 3375-3425) (ABIN7452220)

SPEN 适用: 人 IP 宿主: 兔 Polyclonal unconjugated

SPEN 抗体 by Grade

Find SPEN 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SPEN 抗体 by 适用

Find SPEN 抗体 for a variety of species such as anti-Human SPEN, anti-Mouse SPEN, anti-Dog SPEN. The species listed below are among those available. Click on a link to go to the corresponding products.

SPEN 抗体 by 应用范围

Find SPEN 抗体 validated for a specific application such as IP, ELISA, IF, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

SPEN 抗体 by 抗体来源

Find SPEN 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

SPEN 抗体 by 抗原表位

Find SPEN 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

SPEN 抗体 by 克隆形成能力

Find available monoclonal or polyclonal SPEN 抗体. Click on a link to go to the corresponding products.

Popular SPEN 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN185595
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IP
Validations
Cat. No. ABIN7451040
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IP
Validations
Cat. No. ABIN7452220
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA
Validations
Cat. No. ABIN7096817
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application IP
Validations
Cat. No. ABIN1937728
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Guinea Pig, Horse, Human, Mouse, Rabbit
Application IP
Validations
Cat. No. ABIN1937727
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC (p)
Validations
  • (2)
Cat. No. ABIN5588624
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our SPEN 抗体

Korfanty, Stokowy, Chadalski, Toma-Jonik, Vydra, Widłak, Wojtaś, Gielniewski, Widlak: "SPEN protein expression and interactions with chromatin in mouse testicular cells." in: Reproduction (Cambridge, England), Vol. 156, Issue 3, pp. 195-206, (2018) (PubMed).

McHugh, Chen, Chow, Surka, Tran, McDonel, Pandya-Jones, Blanco, Burghard, Moradian, Sweredoski, Shishkin, Su, Lander, Hess, Plath, Guttman: "The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3." in: Nature, Vol. 521, Issue 7551, pp. 232-6, (2015) (PubMed).

Hiriart, Gruffat, Buisson, Mikaelian, Keppler, Meresse, Mercher, Bernard, Sergeant, Manet: "Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export." in: The Journal of biological chemistry, Vol. 280, Issue 44, pp. 36935-45, (2005) (PubMed).

Aliases for SPEN 抗体

spen family transcriptional repressor (SPEN) 抗体
SPEN homolog, transcriptional regulator (Drosophila) (Spen) 抗体
HIAA0929 抗体
MINT 抗体
Mint 抗体
mKIAA0929 抗体
RBM15C 抗体
SHARP 抗体
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