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SPEN 抗体 (AA 3375-3425)

SPEN 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452220
发货至: 中国
  • 抗原 See all SPEN 抗体
    SPEN (Spen Homolog, Transcriptional Regulator (SPEN))
    抗原表位
    • 2
    • 1
    • 1
    AA 3375-3425
    适用
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 5
    • 1
    克隆类型
    • 6
    多克隆
    标记
    • 6
    This SPEN antibody is un-conjugated
    应用范围
    • 3
    • 2
    • 1
    • 1
    Immunoprecipitation (IP)
    原理
    Rabbit anti-SHARP Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    between AA 3375 and 3425
    亚型
    IgG
    Top Product
    Discover our top product SPEN Primary Antibody
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. ABIN7451040 can be used successfully for WB of enriched preparations (e.g. immunoprecipitated) SHARP.

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    SPEN (Spen Homolog, Transcriptional Regulator (SPEN))
    别名
    SHARP (SPEN 产品)
    别名
    HIAA0929 antibody, MINT antibody, RBM15C antibody, SHARP antibody, Mint antibody, mKIAA0929 antibody, spen family transcriptional repressor antibody, SPEN homolog, transcriptional regulator (Drosophila) antibody, SPEN antibody, Spen antibody
    背景
    Background: SHARP functions as a transcriptional repressor by interacting with proteins involved in deacetylation such as the NuRD (nucleosome remodeling) complex. SHARP can also repress transcription by interacting with corepressors such as SMRT/NCoR (silencing mediator for retinoid and thyroid receptors/nuclear receptor corepressor). SHARP is able to suppress transcription through the Notch/RBP-J signaling pathway by competing RBP-J binding with the intracellular domain of Notch.
    基因ID
    23013
    NCBI登录号
    NP_055816
    UniProt
    Q96T58
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