anti-SET Domain Containing 6 (SETD6) 抗体

Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity (By similarity).. 再加上,我们可以发SETD6 蛋白 (10)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SETD6 79918 Q8TBK2
SETD6 66083 Q9CWY3
SETD6 291844 D3ZSK5
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antibodies-online.cn销售最多的anti-SETD6 抗体

Showing 10 out of 42 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 WB WB Suggested Anti-SETD6 Antibody Titration:  0.2-1 ug/ml  Positive Control:  THP-1 cell lysate 100 μL 2至3个工作日
$289.00
详细
非结合性 WB 100 μL 11至14个工作日
$551.83
详细
非结合性 IC, IF, WB Immunofluorescent analysis of SETD6 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Western blot analysis of SETD6 expression in THP1 (A) whole cell lysates. 200 μL 13至14个工作日
$487.50
详细
非结合性 IHC (p), WB Western blot analysis of SETD6 Antibody in WiDr cell line lysates (35ug/lane) SETD6 Antibody IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2至3个工作日
$515.63
详细
非结合性 IHC, WB Western blot analysis of extracts of THP-1 cells, using SETD6 antibody. Immunofluorescence analysis of A549 cell using SETD6 antibody. Blue: DAPI for nuclear staining. 100 μL 11至13个工作日
$366.77
详细
非结合性 WB Western blot analysis of extracts of THP-1 cells, using SETD6 antibody (ABIN2970694) at 1/1000 dilution. 100 μL 11至16个工作日
$426.40
详细
非结合性 IHC (p), WB Immunohistochemical staining of human pancreas with SETD6 polyclonal antibody  shows strong cytoplasmic positivity in exocrine glandular cells and islets of Langerhans. Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with SETD6 polyclonal antibody . 100 μL 11至12个工作日
$577.33
详细
非结合性 IF/ICC, WB 100 μL 11至18个工作日
$383.76
详细
非结合性 IF, IHC, WB   100 μL 11至14个工作日
$478.50
详细
Biotin IHC, ELISA, WB   200 μL 11至14个工作日
$1,101.83
详细

更多抗SETD6的相互作用对抗体

Human SET Domain Containing 6 (SETD6) interaction partners

  1. Study demonstrates that SETD6 monomeric, dimeric and trimeric forms are stabilized by the methyl donor, S-adenosyl-l-methionine. SETD6 has auto-methylation activity at K39 and K179, which serves as the major auto-methylation sites with a moderate auto-methylation activity toward K372. Data support a model by which SETD6 auto-methylation and self-interaction positively regulate its enzymatic activity in vitro.

  2. During mitosis SETD6 binds and methylates PLK1

  3. WDR5 was identified as a substrate of SETD6 and it was revealed that the methylation of specific lysines (K207/K325) of WDR5 was critical for maintaining global histone H3K4me3 levels and promoting breast cancer cell proliferation and migration

  4. Findings suggest that the identified mutation impairs the normal function of SETD6, which may result in the deregulation of the different pathways in which it is involved, contributing to the increased susceptibility to cancer in this FCCTX family.

  5. High SETD6 expression is associated with bladder cancer.

  6. PAK4 methylation by SETD6 promotes the activation of the Wnt/beta-catenin pathway.

  7. these findings demonstrate that SETD6 negatively regulates the Nrf2-mediated oxidative stress response through a physical and catalytically independent interaction with DJ1 at chromatin.

  8. Several chromatin proteins that associate with SETD6 are identified and SETD6 is described as an essential factor for nuclear receptor signaling and cellular proliferation.

  9. SETD6 monomethylates H2AZ on lysine 7.

  10. SETD6 mono-methylate Rela on K310 and negatively regulates RelA transcription activity

Mouse (Murine) SET Domain Containing 6 (SETD6) interaction partners

  1. SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal.

SETD6 抗原简介

蛋白简介

Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity (By similarity).

Gene names and symbols associated with SETD6

  • SET domain containing 6 (SETD6) 抗体
  • SET domain containing 6 (Setd6) 抗体
  • SET domain containing 6 (setd6) 抗体
  • SET domain containing 6 L homeolog (setd6.L) 抗体
  • 0610039J04Rik 抗体
  • 3110004G14Rik 抗体
  • AI413388 抗体
  • C76402 抗体
  • RGD1560538 抗体
  • wu:fb58f11 抗体
  • zgc:55627 抗体

Protein level used designations for SETD6

SET domain containing 6 , N-lysine methyltransferase SETD6 , SET domain-containing protein 6 , N-lysine methyltransferase setd6

GENE ID SPECIES
100229419 Taeniopygia guttata
79918 Homo sapiens
66083 Mus musculus
291844 Rattus norvegicus
539651 Bos taurus
415675 Gallus gallus
100306753 Salmo salar
443830 Xenopus laevis
322348 Danio rerio
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