SET Domain Containing (Lysine Methyltransferase) 8 抗体
(SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).
Recommended next Filters:
您想试用我们的人工智能搜索吗？
46 results :
SETD8
适用: 人
WB, IF, IHC (p)
宿主: 小鼠
Monoclonal
43AT551-86
unconjugated
1 reference
SETD8
适用: 人
WB, IHC (p), FACS
宿主: 兔
Polyclonal
RB18964
unconjugated
SETD8
适用: 人, 小鼠
WB, IHC (p)
宿主: 兔
Polyclonal
RB1415
unconjugated
Latest Publications for our SET Domain Containing (Lysine Methyltransferase) 8 抗体
: "Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8." in: Biochemistry, Vol. 47, Issue 25, pp. 6671-7, (2010) (PubMed).: "Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation." in: PLoS ONE, Vol. 2, Issue 8, pp. e763, (2010) (PubMed).
: "An miR-502-binding site single-nucleotide polymorphism in the 3'-untranslated region of the SET8 gene is associated with early age of breast cancer onset." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 19, pp. 6292-300, (2009) (PubMed).
: "Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability." in: The Journal of biological chemistry, Vol. 283, Issue 28, pp. 19478-88, (2008) (PubMed).
: "PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin." in: Molecular cell, Vol. 9, Issue 6, pp. 1201-13, (2002) (PubMed).
: "Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase." in: Current biology : CB, Vol. 12, Issue 13, pp. 1086-99, (2002) (PubMed).
Aliases for SET Domain Containing (Lysine Methyltransferase) 8 抗体
lysine methyltransferase 5A (KMT5A) 抗体lysine methyltransferase 5A (Kmt5a) 抗体
lysine methyltransferase 5Ab (kmt5ab) 抗体
lysine methyltransferase 5A S homeolog (kmt5a.S) 抗体
lysine methyltransferase 5Aa (kmt5aa) 抗体
2410195B05Rik 抗体
AA617402 抗体
AW536475 抗体
KMT5A 抗体
kmt5a 抗体
kmt5a-a 抗体
PR-Set7 抗体
PR-SET7 抗体
Pr-set7 抗体
RGD1305893 抗体
SET07 抗体
SET8 抗体
set8a 抗体
Setd8 抗体
setd8 抗体
setd8-a 抗体
setd8a 抗体
setd8b 抗体
wu:fc23f12 抗体
wu:fj33f02 抗体
zgc:153719 抗体
zgc:171649 抗体
您还需要查找其他产品吗？
- SET Binding Factor 2 抗体
- SET and MYND Domain Containing 2a 抗体
- SET and MYND Domain Containing 1 抗体
- Sestrin 2 抗体
- SESTD1 抗体
- SESN3 抗体
- SESN1 抗体
- Seryl-tRNA Synthetase 抗体
- serum/glucocorticoid Regulated Kinase 2 抗体
- serum/glucocorticoid Regulated Kinase 1 抗体
- SERTAD3 抗体
- SERTAD2 抗体
- SERTAD1 抗体
- SERPINI2 抗体
- SERPINH1 抗体
- SERPING1 抗体
- SERPINE2 抗体
- SERPIND1 抗体
- SERPINC1 抗体
- SERPINB9 抗体
You are here:
