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The protein encoded by P2RX6 belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations.
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one subunit of P2X2 (显示 P2RX2 抗体) and two subunits of P2X3 (显示 P2RX3 抗体) form P2X2 (显示 P2RX2 抗体)/3 heteromeric receptors, whereas two subunits of P2X2 (显示 P2RX2 抗体) and one subunit of P2X6 constitute P2X2 (显示 P2RX2 抗体)/6 receptors
Results show that P2X4 (显示 P2RX4 抗体) and P2X6 receptors are associated with VE-cadherin (显示 CDH5 抗体) at HUVEC adherens junctions.
purinergic signaling via P2X6 is not significantly involved in the regulation of renal electrolyte handling under normal physiological conditions.
once inside the nucleus, P2X6 subunit interacts with the splicing factor 3A1 (显示 SF3A1 抗体), which ultimately results in a reduction of the mRNA splicing activity
Immunoreactivity for P2X3 (显示 P2RX3 抗体)-, P2X5 (显示 P2RX5 抗体)-, and P2X6-purinoceptors was observed in mouse retina.
This study provides the first evidence that P2X8 receptors are expressed on LHRH (显示 GNRH1 抗体)-containing neurons.
The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.
, P2X purinoceptor 6
, purinergic receptor P2X-like 1, orphan receptor
, purinoceptor P2X6
, purinoreceptor P2X6
, skeletal muscle-expressed P2X
, purinergic receptor P2X, ligand-gated ion channel, 6
, P2X purinoceptor 6-like
, p2X purinoceptor 6-like
, P2X6 receptor
, purinergic receptor P2X-like 1 orphan receptor
, purinergic receptor P2X6