anti-Prolylcarboxypeptidase (PRCP) 抗体

The protein encoded by PRCP is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. 再加上,我们可以发Prolylcarboxypeptidase 试剂盒 (44)Prolylcarboxypeptidase 蛋白 (12)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
PRCP 72461 Q7TMR0
PRCP 5547 P42785
PRCP 293118  
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining; Read the data in MicroplateReader by 450nm. Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in Microplate Reader by 450nm 100 μL Log in to see 3至7个工作日
$306.90
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非结合性 IHC, WB Western blot analysis of extract of rat kidney cells, using PRCP antibody. 100 μL Log in to see 16 Days
$476.15
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大鼠 非结合性 ICC, IHC, IP, WB DAB staining on IHC-P; Samples: Rat Lung Tissue 100 μg Log in to see 13至16个工作日
$362.00
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Alexa Fluor 647 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
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Alexa Fluor 555 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
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Alexa Fluor 488 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
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Alexa Fluor 350 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
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Cy5 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
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FITC IF (p)   100 μL Log in to see 14至21个工作日
$405.90
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HRP IHC (p), WB   100 μL Log in to see 14至21个工作日
$405.90
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通过反应活性、应用领域、克隆类型和共轭标记 PRCP 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine) ,


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更多抗Prolylcarboxypeptidase的相互作用对抗体

Mouse (Murine) Prolylcarboxypeptidase (PRCP) interaction partners

  1. This study demonistrated that PRCP gene is broadly expressed in the brain.

  2. PRCP regulates cell growth, angiogenesis, and the response to vascular injury

  3. ACE2 (显示 ACE2 抗体) metabolizes ANG II (显示 AGT 抗体) in the kidney at neutral and basic pH, while prolylcarboxypeptidase catalyzes the same reaction at acidic pH.

  4. PRCP is an important regulator of energy and glucose homeostasis since its deletion significantly improves metabolic parameters in mice exposed to both standard chow diet and high-fat diet

  5. analysis of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors

  6. This study showed that PRCP mutant mice have a significant decrease in fat mass, although an increase in lean mass was also observed; reduced leptin (显示 LEP 抗体) levels and increased energy expenditure were also found.

  7. Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis.

  8. PRCP is an important component of melanocortin signaling and weight maintenance via control of active alpha-MSH1-13 levels.

Human Prolylcarboxypeptidase (PRCP) interaction partners

  1. For the first time, PRCP is identified as an apelin (显示 APLN 抗体)-cleaving enzyme.

  2. The decrease in PRCP levels in the first 24 h after stroke onset is associated with stroke severity and an unfavourable short-term stroke outcome

  3. PRCP1 interacts with plasma kallikrein (显示 KLKB1 抗体) (PK) at multiple sites for PK activation.

  4. The present results indicated PRCP rs7104980 can be considered as a marker for EH and Hap3 GAGCACTAACA (PRCP) and Hap16 TTTA (CMA1) might be associated with essential hypertension in Chinese Han population.

  5. PRCP regulates cell growth, angiogenesis, and the response to vascular injury

  6. analysis of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors

  7. PRCP as a resistance factor for 4OHTAM resistance in estrogen receptor (显示 ESR1 抗体)-positive breast cancer cells.

  8. A single peptide, with the sequence YPRPIHPA, as a novel substrate for PRCP in human cerebrospinal fluid.

  9. Purified PrCP yielded crystals belonging to space group R32, with unit-cell parameters a = b = 181.14, c = 240.13 A, that diffracted to better than 2.8 A resolution.

  10. A structure-based alignment with the previously undescribed structure of DPP7 (显示 DPP7 抗体) illuminates the mechanism of orthogonal substrate specificity of PRCP and DPP7 (显示 DPP7 抗体).

Prolylcarboxypeptidase (PRCP) 抗原简介

蛋白简介

The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with PRCP

  • prolylcarboxypeptidase (prcp) 抗体
  • lysosomal Pro-X carboxypeptidase (LOC5579822) 抗体
  • prolylcarboxypeptidase (CpipJ_CPIJ006123) 抗体
  • prolylcarboxypeptidase (CpipJ_CPIJ006124) 抗体
  • prolylcarboxypeptidase (angiotensinase C) (Prcp) 抗体
  • prolylcarboxypeptidase (PRCP) 抗体
  • prolylcarboxypeptidase (Prcp) 抗体
  • prolylcarboxypeptidase (angiotensinase C) (prcp) 抗体
  • 2510048K03Rik 抗体
  • 2610104A14Rik 抗体
  • AI451719 抗体
  • HUMPCP 抗体
  • MGC145178 抗体
  • PCP 抗体
  • zgc:91816 抗体

Protein level used designations for PRCP

prolylcarboxypeptidase , lysosomal Pro-X carboxypeptidase , proline carboxypeptidase , angiotensinase C , lysosomal carboxypeptidase C , prolylcarboxypeptidase isoform 1 preproprotein

GENE ID SPECIES
780095 Xenopus (Silurana) tropicalis
5579822 Aedes aegypti
6038068 Culex quinquefasciatus
6038069 Culex quinquefasciatus
72461 Mus musculus
5547 Homo sapiens
534927 Bos taurus
293118 Rattus norvegicus
476788 Canis lupus familiaris
100061830 Equus caballus
100734342 Cavia porcellus
436967 Danio rerio
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