anti-Ornithine Aminotransferase (OAT) 抗体

OAT encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. 再加上,我们可以发OAT 试剂盒 (15)OAT 蛋白 (14)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
OAT 18242 P29758
OAT 64313 P04182
OAT 4942 P04181
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antibodies-online.cn销售最多的anti-OAT 抗体

Showing 10 out of 79 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-OAT Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  293T cell lysate OAT is supported by BioGPS gene expression data to be expressed in HEK293T Host:  Rabbit  Target Name:  OAT  Sample Type:  Human Fetal Liver  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2至3个工作日
$289.00
详细
小鼠 非结合性 EIA, IF, WB 0.1 mL Log in to see 6至8个工作日
$412.50
详细
Cow 非结合性 IHC, WB WB Suggested Anti-OAT Antibody Titration:  5.0ug/ml  Positive Control:  HepG2 cell lysate Sample Type :  Pig duodenum   Primary Antibody Dilution :   1:500  Secondary Antibody :  Anti-rabbit-biotin, streptavidin-HRP   Secondary Antibody Dilution :   1:500  Color/Signal Descriptions :  Brown: OAT  Gene Name :  OAT   Submitted by :  Juan C. Mari, USDA/ARS Children's Nutrition Research Center Baylor College of Medicine 100 μL Log in to see 2至3个工作日
$229.00
详细
非结合性 FACS, IF, IHC (p), WB Western blot analysis of OAT Antibody (N-term) (ABIN652844) in 293, MDA-MB231 cell line lysates (35 µg/lane). OAT (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with OAT Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10至11个工作日
$385.00
详细
非结合性 ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human gastric cancer, using OAT, antibody at 1:100 dilution. WB Image Sample(30 ug whole cell lysate) A:293T 7.5% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 3至4个工作日
$466.18
详细
非结合性 IC, IF, WB Immunofluorescent analysis of OAT staining in Raw264.7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of OAT expression in A549 (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 ICC, IF, IHC (p), IHC, WB Immunohistochemistry-Paraffin: OAT Antibody [NBP1-32390] - Paraffin-embedded Gastric CA, using antibody at 1:100 dilution. Immunocytochemistry/Immunofluorescence: OAT Antibody [NBP1-32390] - Analysis of methanol-fixed A431, using antibody at 1:200 dilution. 100 μL Log in to see 8至11个工作日
$516.98
详细
非结合性 ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Porcine Liver Tissue; Lane2: Porcine Kidney Tissue; Lane3: Rat Testis Tissue; Lane4: Rat Pancreas Tissue. Figure. Western Blot; Sample: Recombinant OAT, Human. 100 μg Log in to see 13至16个工作日
$350.00
详细
小鸡 非结合性 WB 100 μg Log in to see 11至14个工作日
$493.17
详细
Cow 非结合性 WB 50 μg Log in to see 11至14个工作日
$551.83
详细

引用最多的anti-OAT 抗体

  1. Cow (Bovine) Polyclonal OAT Primary Antibody for WB - ABIN2783233 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

更多抗OAT的相互作用对抗体

Mouse (Murine) Ornithine Aminotransferase (OAT) interaction partners

  1. The data highlight the importance of OAT in ornithine metabolism, especially in the liver, and suggest a post-transcriptional regulation of OAT by LPS in the liver.

  2. in female and castrated male mice devoided of testosterone, OAT gene is highly expressed and L-ornithine is converted into L-glutamate.

  3. In H4Flox liver, glutamine synthetase (GS), ornithine aminotransferase (OAT) and thyroid hormone-receptor beta1 (TRbeta1) were exclusively expressed in pericentral hepatocytes.

  4. Sexual dimorphism of Oat expression in the kidney was observed.

Human Ornithine Aminotransferase (OAT) interaction partners

  1. OAT Val332-to-Met substitution identified in pyridoxine-responsive gyrate atrophy patients does not significantly affect the spectroscopic and kinetic properties of OAT, but during catalysis it makes the protein prone to convert into the apo-form, which undergoes unfolding and aggregation under physiological conditions.

  2. identified Arg217 as an important hot-spot at the dimer-dimer interface of hOAT and demonstrated that the artificial dimeric variant R217A exhibits spectroscopic properties, Tm values and catalytic features similar to those of the tetrameric species. This finding indicates that the catalytic unit of hOAT is the dimer.

  3. Sequencing of the gene for ornithine aminotransferase reveals a homozygous mutation in our patient (base exchange c.498C>A in Exon 4).

  4. Neurogenesis is inhibited by X-OAT during Xenopus embryonic development, but it is essential for Xenopus embryonic development. The Arg 180 and Leu 402 are crucial for these effects of the OAT molecule in development.

  5. Our report describes the first case of gyrate atrophy in the Korean population diagnosed by OAT gene analysis and treated with vitamin B6 dietary supplementation.

  6. We identified a novel frameshift mutation (p.K169DfsX10) in the OAT gene. While an early arginine-restricted dietary treatment suppressed the fundus changes

  7. Data suggest that other factors besides the specific ornithine aminotransferase (OAT) genotype modulate atrophy of choroid and retina (GA) phenotype in patients.

  8. OAT was a highly homologous and stable protein located in the mitochondria.

  9. Molecular analysis revealed a new deletion c.532_536delTGGGG (p.Trp178X) and a known mutation c.897C>G (p.Tyr299X) in the OAT gene.

  10. Fundus autofluorescence imaging can reveal the extent of neurosensory dysfunction in gyrate atrophy patients.

  11. analysis of ornithine aminotransferase substrate specificity

OAT 抗原简介

蛋白简介

This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.

Gene names and symbols associated with OAT

  • Ornithine aminotransferase precursor (Oat) 抗体
  • ornithine aminotransferase, gene 1 (oat.1) 抗体
  • ornithine aminotransferase (OAT) 抗体
  • ornithine aminotransferase (Lbys_2951) 抗体
  • ornithine aminotransferase (Riean_0998) 抗体
  • ornithine aminotransferase (Ftrac_2019) 抗体
  • ornithine aminotransferase (Celal_2605) 抗体
  • ornithine aminotransferase (Deipr_1149) 抗体
  • ornithine aminotransferase (Celly_0230) 抗体
  • ornithine aminotransferase (Weevi_2065) 抗体
  • ornithine aminotransferase (Fluta_4071) 抗体
  • ornithine aminotransferase (Halhy_2848) 抗体
  • ornithine aminotransferase (Theth_0565) 抗体
  • ornithine aminotransferase (oat) 抗体
  • ornithine aminotransferase (Oat) 抗体
  • 151832_at 抗体
  • AI194874 抗体
  • CG8782 抗体
  • Dmel\\CG8782 抗体
  • GACR 抗体
  • HOGA 抗体
  • OATASE 抗体
  • OKT 抗体
  • rOAT 抗体

Protein level used designations for OAT

CG8782-PA , Oat-PA , ornithine aminotransferase , ornithine aminotransferase precursor , ornithine aminotransferase (gyrate atrophy) , ornithine aminotransferase, mitochondrial , ornithine--oxo-acid aminotransferase , gyrate atrophy , ornithine delta-aminotransferase , ornithine-oxo-acid aminotransferase

GENE ID SPECIES
40145 Drosophila melanogaster
379754 Xenopus laevis
450803 Pan troglodytes
477858 Canis lupus familiaris
9956831 Leadbetterella byssophila DSM 17132
10001754 Riemerella anatipestifer ATCC 11845 = DSM 15868
10012165 Marivirga tractuosa DSM 4126
10145026 Cellulophaga algicola DSM 14237
10256630 Deinococcus proteolyticus MRP
10262214 Cellulophaga lytica DSM 7489
10283330 Weeksella virosa DSM 16922
10399445 Fluviicola taffensis DSM 16823
10587022 Haliscomenobacter hydrossis DSM 1100
10885318 Thermotoga thermarum DSM 5069
100337582 Xenopus laevis
18242 Mus musculus
64313 Rattus norvegicus
4942 Homo sapiens
505323 Bos taurus
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