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OAS1B 抗体

(2'-5' Oligoadenylate Synthetase 1B (OAS1B))

This gene is a member of the 2'-5' oligoA synthetase family, which are clustered on chromosome 5. The encoded protein functions in the interferon-regulated OAS/RNase L system, which mediates RNA decay as part of the innate antiviral immunity pathway. The protein binds double-stranded RNA and oligomerizes ATP, which activate the single-stranded RNA cleavage enzyme RNase L. This protein mediates resistance to flaviviruses such as West Nile virus. The majority of wild mouse strains produce a functional protein and are resistant to flavivirus infection, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a premature stop codon that inactivates this gene product. [provided by RefSeq, Jul 2008].

recommended

OAS1B 抗体 (C-Term) (ABIN2477148)

OAS1B 适用: West Nile Virus (WNV) IF, ELISA, WB 宿主: 兔 Polyclonal unconjugated

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Popular OAS1B 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-OAS1B 抗体 (C-Term)

Reactivity West Nile Virus (WNV)

Application IF, ELISA, WB

Validations

Cat. No. ABIN2477148

Quantity 0.1 mg

Datasheet Datasheet

Latest Publications for our OAS1B 抗体

Chu, Rajamanonmani, Li, Bhuvanakantham, Lescar, Ng: "Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein." in: The Journal of general virology, Vol. 86, Issue Pt 2, pp. 405-12, (2005) (PubMed).

Gould, Fikrig: "West Nile virus: a growing concern?" in: The Journal of clinical investigation, Vol. 113, Issue 8, pp. 1102-7, (2004) (PubMed).

Chu, Ng: "Interaction of West Nile virus with alpha v beta 3 integrin mediates virus entry into cells." in: The Journal of biological chemistry, Vol. 279, Issue 52, pp. 54533-41, (2004) (PubMed).

Aliases for OAS1B 抗体

2'-5' oligoadenylate synthetase 1B (Oas1b) 抗体
2-5 oligoadenylate synthetase 1B (Oas1b) 抗体
(2-5')oligo(A) synthase 1B 抗体
2-5A synthase 1B 抗体
Flv 抗体
L1 抗体
Mmu-L1 抗体
Oas1 抗体
Oias-2 抗体
Oias2 抗体
Wnv 抗体

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