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anti-NPC1 抗体

NPC1 encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain.

50 results:

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) (AA 34-174) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 FACS, IHC, ELISA, WB 宿主: 小鼠 Monoclonal
产品编号 ABIN1845969
$464.30
加上运输费 $45.00
100 μg
local_shipping 发货至: 美国
11至16个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) (AA 591-620) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 IF, IHC, ELISA, WB 宿主: 兔 Polyclonal
产品编号 ABIN3031998
$452.38
加上运输费 $45.00
0.4 mL (More quantities available)
local_shipping 发货至: 美国
2至3个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) (AA 34-174) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 IHC, ELISA, WB 宿主: 小鼠 Monoclonal 8D10B6
Pubmed 2
产品编号 ABIN1724876
$430.10
加上运输费 $45.00
0.1 mg
local_shipping 发货至: 美国
3至4个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) (C-Term) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 ELISA, FM, IHC, WB 宿主: 兔 Polyclonal
产品编号 ABIN6655360
$369.00
Plus shipping costs $45.00 and $22.00 dry ice
100 μg
local_shipping 发货至: 美国
1至2个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 IF, IHC, IHC (p), IP, WB 宿主: 小鼠 Monoclonal
产品编号 ABIN462125
$727.83
加上运输费 $45.00
50 μg
local_shipping 发货至: 美国
11至14个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) (Internal Region) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal
产品编号 ABIN1590132
$429.87
加上运输费 $45.00
100 μg
local_shipping 发货至: 美国
6至7个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) (C-Term) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 EIA, IHC (p), WB 宿主: 兔 Polyclonal
产品编号 ABIN500383
$500.50
加上运输费 $45.00
0.1 mg
local_shipping 发货至: 美国
6至8个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: IEM, IF, IHC, IP, WB 宿主: 兔 Polyclonal
Pubmed 3
产品编号 ABIN540364
$542.86
加上运输费 $45.00
100 μL
local_shipping 发货至: 美国
11至12个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) (C-Term) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人, 小鼠 ELISA, IHC, IHC (p), WB 宿主: 兔 Polyclonal
产品编号 ABIN959667
$616.00
加上运输费 $45.00
50 μg
local_shipping 发货至: 美国
11至14个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) (Internal Region) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 小鼠 ELISA 宿主: 山羊 Polyclonal
产品编号 ABIN570865
$278.78
加上运输费 $45.00
100 μg
local_shipping 发货至: 美国
6至7个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 WB 宿主: 兔 Polyclonal
产品编号 ABIN1681082
$393.25
加上运输费 $45.00
100 μg (More quantities available)
local_shipping 发货至: 美国
13至14个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal
产品编号 ABIN2147755
$517.86
加上运输费 $45.00
50 μL
local_shipping 发货至: 美国
9至11个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) (AA 1022-1278) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal
产品编号 ABIN5693129
$240.00
加上运输费 $45.00
100 μg
local_shipping 发货至: 美国
4至6个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) (AA 151-250) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4H2
产品编号 ABIN562034
$440.00
加上运输费 $45.00
100 μg
local_shipping 发货至: 美国
11至12个工作日

anti-NPC1 抗体 (Niemann-Pick Disease, Type C1) (AA 372-622) Primary Antibody

Synonym: NPC intracellular cholesterol transporter 1 NPC1 适用: 人 ELISA 宿主: 兔 Polyclonal
产品编号 ABIN6923952
$183.12
加上运输费 $45.00
100 μL (More quantities available)
local_shipping 发货至: 美国
14至16个工作日
  • 类型 Primary
    • Primary
  • 抗原 Niemann-Pick Disease, Type C1 (NPC1)
    • Niemann-Pick Disease, Type C1 (NPC1)
    • Histone 3 (H3)
    • Tumor Protein P53 (TP53)
    • Epidermal Growth Factor Receptor (EGFR)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • tau Protein
    • CD4 Molecule (CD4)
    • Tumor Necrosis Factor alpha (TNF)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Estrogen Receptor 1 (ESR1)
    • Nuclear Factor-KB P65 (NFkBP65)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • Interferon gamma (IFNG)
    • Albumin (ALB)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • Heat Shock Protein 70 (HSP70)
    • Amyloid beta (A4) Precursor Protein (APP)
    • CD44
    • Tuberous Sclerosis 2 (TSC2)
    • Myc Proto-Oncogene protein (MYC)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • CD19 Molecule (CD19)
    • Histone H4
    • CD8a Molecule (CD8A)
    • Synuclein, alpha (SNCA)
    • Hemagglutinin (HA)
    • Integrin alpha M (ITGAM)
    • CD3e Molecule, epsilon (CD3-TCR Complex) (CD3E)
    • Jun Proto-Oncogene (JUN)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • CD8
    • Interleukin 6 (IL6)
    • Vimentin (VIM)
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • CD5 Molecule (CD5)
    • Glial Fibrillary Acidic Protein (GFAP)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Heat Shock 27kDa Protein 1 (HSPB1)
    • Mucin 1, Cell Surface Associated (MUC1)
    • CD3
    • Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1)
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Interleukin 2 (IL2)
    • Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)
    • CD14
    • CD34
    • Cyclin-Dependent Kinase 1 (CDK1)
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • Immunohistochemistry (IHC)
    • Immunofluorescence (IF)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunocytochemistry (ICC)
    • Flow Cytometry (FACS)
    • Immunoprecipitation (IP)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Enzyme Immunoassay (EIA)
    • Fluorescence Microscopy (FM)
    • Immunoelectron Microscopy (IEM)
    • Immunofluorescence (Cultured Cells) (IF (cc))
  • 适用
    • 小鼠
    • 大鼠
  • 论文引用
  • 图像
  • 抗体来源
    • 山羊
    • 小鼠
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 14i194
    • 1B12
    • 4H2
    • 8D10B6
  • 抗原表位
    • Internal Region
    • AA 590-620
    • Center
    • AA 591-620
    • C-Term
    • AA 23-269
    • AA 34-174
    • AA 1022-1278
    • AA 151-250
    • AA 372-622
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • APC
    • Alkaline Phosphatase (AP)
    • HRP
    • PE
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
  • 抗体亚型
    • IgG
    • IgG1
    • Ig Fraction
    • IgG2a kappa
  • Format
    • Liquid
    • Lyophilized

NPC1 抗原简介

蛋白简介

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.

Gene names and symbols associated with NPC1

  • NPC intracellular cholesterol transporter 1 (NPC1) 抗体
  • Niemann-Pick disease, type C1 (npc1) 抗体
  • Niemann-Pick C1 protein (LOC579887) 抗体
  • NPC intracellular cholesterol transporter 1 (Npc1) 抗体
  • A430089E03Rik 抗体
  • C85354 抗体
  • Cdig2 抗体
  • D18Ertd139e 抗体
  • D18Ertd723e 抗体
  • im:7149020 抗体
  • lcsd 抗体
  • nmf164 抗体
  • NPC 抗体
  • spm 抗体
  • wu:fb53a12 抗体
  • wu:fc29a12 抗体

Protein level used designations for NPC1

Niemann-Pick C1 protein , Niemann-Pick type C1 disease protein , Nasopharyngeal carcinoma 1 , Niemann-Pick C1 , Niemann-Pick disease, type C1 , sphingomyelinosis , Niemann-Pick C disease protein

GENE ID SPECIES
403698 Canis lupus familiaris
455338 Pan troglodytes
493693 Felis catus
553330 Danio rerio
579887 Strongylocentrotus purpuratus
100008746 Oryctolagus cuniculus
18145 Mus musculus
4864 Homo sapiens
397591 Sus scrofa
421076 Gallus gallus
266732 Rattus norvegicus
100718604 Cavia porcellus
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