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NHEJ1 抗体

(Nonhomologous End-Joining Factor 1 (NHEJ1))
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008].
NHEJ1 抗体 NHEJ1 抗体 NHEJ1 抗体 (ABIN1499728)

NHEJ1 适用: 人, 猴 WB, IF, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3D6 unconjugated

NHEJ1 抗体 NHEJ1 抗体 NHEJ1 抗体 (ABIN7261171)

NHEJ1 适用: 人, 大鼠, 小鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated

NHEJ1 抗体 NHEJ1 抗体 NHEJ1 抗体 (ABIN2857060)

NHEJ1 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated

NHEJ1 抗体 by Grade

Find NHEJ1 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

NHEJ1 抗体 by 适用

Find NHEJ1 抗体 for a variety of species such as anti-Human NHEJ1, anti-Rat NHEJ1, anti-Monkey NHEJ1. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find NHEJ1 抗体 validated for a specific application such as WB, ELISA, IF, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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NHEJ1 抗体 by 抗原表位

Find NHEJ1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

NHEJ1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal NHEJ1 抗体. Click on a link to go to the corresponding products.

NHEJ1 抗体 by 克隆

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NHEJ1 抗体 by 标记

Find NHEJ1 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular NHEJ1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Monkey
Application WB, IF, IHC, FACS, IHC (p)
Validations
  • (15)
Cat. No. ABIN1499728
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IHC
Validations
  • (5)
Cat. No. ABIN7261171
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), IP, ICC
Validations
  • (4)
Cat. No. ABIN2857060
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN529086
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN185719
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7161682
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6747627
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7161685
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7161684
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7161683
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IP, IHC (fp)
Validations
Cat. No. ABIN7454372
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN1811873
Quantity 400 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Rat
Application WB, IF, IHC, FACS, IHC (p)
Validations
Cat. No. ABIN2586212
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP, IHC (fp)
Validations
Cat. No. ABIN7453811
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Application IHC
Validations
Cat. No. ABIN7448867
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our NHEJ1 抗体

Warmerdam, Alonso-de Vega, Wiegant, van den Broek, Rother, Wolthuis, Freire, van Attikum, Medema, Smits: "PHF6 promotes non-homologous end joining and G2 checkpoint recovery." in: EMBO reports, Vol. 21, Issue 1, pp. e48460, (2020) (PubMed).

Nemoz, Ropars, Frit, Gontier, Drevet, Yu, Guerois, Pitois, Comte, Delteil, Barboule, Legrand, Baconnais, Yin, Tadi, Barbet-Massin, Berger, Le Cam, Modesti, Rothenberg, Calsou, Charbonnier: "XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining." in: Nature structural & molecular biology, Vol. 25, Issue 10, pp. 971-980, (2018) (PubMed).

Tadi, Tellier-Lebègue, Nemoz, Drevet, Audebert, Roy, Meek, Charbonnier, Modesti: "PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF." in: Cell reports, Vol. 17, Issue 2, pp. 541-555, (2016) (PubMed).

Reid, Keegan, Leo-Macias, Watanabe, Strande, Chang, Oksuz, Fenyo, Lieber, Ramsden, Rothenberg: "Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 20, pp. E2575-84, (2015) (PubMed).

Liu, Liu, Kamdar, Wanotayan, Sharma, Adachi, Matsumoto: "C-Terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin." in: Biochemical and biophysical research communications, Vol. 439, Issue 2, pp. 173-8, (2013) (PubMed).

Dutrannoy, Demuth, Baumann, Schindler, Konrat, Neitzel, Gillessen-Kaesbach, Radszewski, Rothe, Schellenberger, Nürnberg, Nürnberg, Teik, Nallusamy, Reis, Sperling, Digweed, Varon: "Clinical variability and novel mutations in the NHEJ1 gene in patients with a Nijmegen breakage syndrome-like phenotype." in: Human mutation, Vol. 31, Issue 9, pp. 1059-68, (2010) (PubMed).

Zha, Alt, Cheng, Brush, Li: "Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 11, pp. 4518-23, (2007) (PubMed).

Wu, Frit, Malivert, Revy, Biard, Salles, Calsou: "Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell." in: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 31937-43, (2007) (PubMed).

Ahnesorg, Smith, Jackson: "XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining." in: Cell, Vol. 124, Issue 2, pp. 301-13, (2006) (PubMed).

Aliases for NHEJ1 抗体

non-homologous end joining factor 1 (NHEJ1) 抗体
non-homologous end joining factor 1 S homeolog (nhej1.S) 抗体
non-homologous end joining factor 1 (nhej1) 抗体
solute carrier family 23 member 3 (SLC23A3) 抗体
nonhomologous end-joining factor 1 (nhej1) 抗体
nonhomologous end-joining factor 1 (Nhej1) 抗体
1700029B21Rik 抗体
cernunnos 抗体
NHEJ1 抗体
XLF 抗体
zgc:85657 抗体
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