电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

NHEJ1 抗体

(Nonhomologous End-Joining Factor 1 (NHEJ1))
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008].

Active filters:

  • 抗原: NHEJ1
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7792332
Recombinant NHEJ1 抗体 (Biotin) NHEJ1 · Primary Antibody 人, 小鼠, 大鼠 兔 Monoclonal
  • WB (Western Blotting: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
  • 100 μL
发货至: 中国
ABIN6859741
NHEJ1 抗体 (Alexa Fluor 750) NHEJ1 · Primary Antibody 人 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6819488
NHEJ1 抗体 (Alexa Fluor 488) NHEJ1 · Primary Antibody 人 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN6835551
NHEJ1 抗体 (Alexa Fluor 594) NHEJ1 · Primary Antibody 人 兔 Polyclonal
  • 100 μL
发货至: 中国
ABIN8123368
NHEJ1 抗体 NHEJ1 · Primary Antibody 人, 小鼠, 大鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • 50 μL
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • ICC (Immunocytochemistry: 所列应用)
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Biotin
蛋白类型
Recombinant Antibody
产品编号 ABIN7792332
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 750
产品编号 ABIN6859741
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 488
产品编号 ABIN6819488
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Alexa Fluor 594
产品编号 ABIN6835551
Primary Antibody
  • WB (Western Blotting: 所列应用)
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
产品编号 ABIN8123368

Latest Publications for our NHEJ1 抗体

Vu, Bonucci, Brenière, Cisneros-Aguirre, Pelupessy, Wang, Carlier, Bouvignies, Cortes, Aggarwal, Blackledge, Gueroui, Belle, Stark, Modesti, Ferrage: "Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro." in: Nature structural & molecular biology, Vol. 31, Issue 11, pp. 1732-1744, (2024) (PubMed).

Warmerdam, Alonso-de Vega, Wiegant, van den Broek, Rother, Wolthuis, Freire, van Attikum, Medema, Smits: "PHF6 promotes non-homologous end joining and G2 checkpoint recovery." in: EMBO reports, Vol. 21, Issue 1, pp. e48460, (2020) (PubMed).

Nemoz, Ropars, Frit, Gontier, Drevet, Yu, Guerois, Pitois, Comte, Delteil, Barboule, Legrand, Baconnais, Yin, Tadi, Barbet-Massin, Berger, Le Cam, Modesti, Rothenberg, Calsou, Charbonnier: "XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining." in: Nature structural & molecular biology, Vol. 25, Issue 10, pp. 971-980, (2018) (PubMed).

Tadi, Tellier-Lebègue, Nemoz, Drevet, Audebert, Roy, Meek, Charbonnier, Modesti: "PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF." in: Cell reports, Vol. 17, Issue 2, pp. 541-555, (2016) (PubMed).

Reid, Keegan, Leo-Macias, Watanabe, Strande, Chang, Oksuz, Fenyo, Lieber, Ramsden, Rothenberg: "Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 20, pp. E2575-84, (2015) (PubMed).

Liu, Liu, Kamdar, Wanotayan, Sharma, Adachi, Matsumoto: "C-Terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin." in: Biochemical and biophysical research communications, Vol. 439, Issue 2, pp. 173-8, (2013) (PubMed).

Dutrannoy, Demuth, Baumann, Schindler, Konrat, Neitzel, Gillessen-Kaesbach, Radszewski, Rothe, Schellenberger, Nürnberg, Nürnberg, Teik, Nallusamy, Reis, Sperling, Digweed, Varon: "Clinical variability and novel mutations in the NHEJ1 gene in patients with a Nijmegen breakage syndrome-like phenotype." in: Human mutation, Vol. 31, Issue 9, pp. 1059-68, (2010) (PubMed).

Zha, Alt, Cheng, Brush, Li: "Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 11, pp. 4518-23, (2007) (PubMed).

Wu, Frit, Malivert, Revy, Biard, Salles, Calsou: "Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell." in: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 31937-43, (2007) (PubMed).

Ahnesorg, Smith, Jackson: "XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining." in: Cell, Vol. 124, Issue 2, pp. 301-13, (2006) (PubMed).

Aliases for NHEJ1 抗体

non-homologous end joining factor 1 (NHEJ1) 抗体
non-homologous end joining factor 1 S homeolog (nhej1.S) 抗体
non-homologous end joining factor 1 (nhej1) 抗体
solute carrier family 23 member 3 (SLC23A3) 抗体
nonhomologous end-joining factor 1 (nhej1) 抗体
nonhomologous end-joining factor 1 (Nhej1) 抗体
1700029B21Rik 抗体
cernunnos 抗体
NHEJ1 抗体
XLF 抗体
zgc:85657 抗体
You are here: