anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) 抗体

LILRB4 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. 再加上,我们可以发LILRB4 试剂盒 (30)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
LILRB4 11006 Q8NHJ6
LILRB4 14728 Q64281
LILRB4    
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antibodies-online.cn销售最多的anti-LILRB4 抗体

Showing 10 out of 79 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IF, ELISA Immunofluorescence analysis of A549 cells, using LILRB4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 EIA, WB Western blot analysis of CD85K / LILRB4 Antibody (N-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the LILRB4 antibody detected the LILRB4 protein (arrow). 0.4 mL Log in to see 6至8个工作日
$390.50
详细
小鼠 PE FACS Detection of LILRB4/CD85k/ILT3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human IL-3 R alpha/CD123 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8至9个工作日
$304.75
详细
非结合性 WB LILRB4 Antibody (N-term) (ABIN656231) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the LILRB4 antibody detected the LILRB4 protein (arrow). 400 μL Log in to see 10至11个工作日
$335.50
详细
小鼠 Fluorescein FACS Detection of LILRB4/CD85k/ILT3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human IL-3 R alpha/CD123 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8至9个工作日
$246.10
详细
非结合性 IHC Immunohistochemistry: ILT3/CD85k/LILRB4 Antibody [NBP2-49063] - Staining of human tonsil shows strong cytoplasmic positivity in subset of non-germinal center cells. Immunohistochemistry-Paraffin: ILT3/CD85k/LILRB4 Antibody  - Staining of human tonsil shows strong cytoplasmic positivity in subset of non-germinal center cells. 0.1 mL Log in to see 34 Days
$491.63
详细
小鼠 非结合性 ICC, IHC, WB Figure . Western Blot; Sample: Rat Adrenal Gland Tissue. 100 μg Log in to see 13至16个工作日
$342.00
详细
小鼠 APC FACS Detection of LILRB4/CD85k/ILT3 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human IL-3 R alpha/CD123 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8至9个工作日
$351.90
详细
山羊 Biotin FACS, WB   50 μg Log in to see 8至9个工作日
$451.95
详细
非结合性 ELISA, IF   100 μL Log in to see 16 Days
$181.73
详细

引用最多的anti-LILRB4 抗体

  1. Human Monoclonal LILRB4 Primary Antibody for FACS - ABIN4895889 : Zimmer, Luce, Gaignier, Nony, Naveau, Biola-Vidamment, Pallardy, Van Overtvelt, Mascarell, Moingeon: Identification of a new phenotype of tolerogenic human dendritic cells induced by fungal proteases from Aspergillus oryzae. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal LILRB4 Primary Antibody for FACS, WB - ABIN4899298 : Waschbisch, Sanderson, Krumbholz, Vlad, Theil, Schwab, Mäurer, Derfuss: Interferon beta and vitamin D synergize to induce immunoregulatory receptors on peripheral blood monocytes of multiple sclerosis patients. in PLoS ONE 2015 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal LILRB4 Primary Antibody for FACS - ABIN4895887 : Ulges, Klein, Reuter, Gerlitzki, Hoffmann, Grebe, Staudt, Stergiou, Bohn, Brühl, Muth, Yurugi, Rajalingam, Bellinghausen, Tuettenberg, Hahn, Reißig, Haben, Zipp, Waisman, Probst, Beilhack, Buchou et al.: Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo. ... in Nature immunology 2015 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal LILRB4 Primary Antibody for CyTOF, FACS - ABIN4899300 : Gleissner, Zastrow, Klingenberg, Kluger, Konstandin, Celik, Haemmerling, Shankar, Giese, Katus, Dengler: IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells. in European journal of immunology 2006 (PubMed)

更多抗LILRB4的相互作用对抗体

Human Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) interaction partners

  1. Results suggest that ILT3 played an important role in tumor progression in colorectal cancer by possible influence on CD45RO+ T cells in the tumor microenvironment.

  2. These results suggest that tyrosine phosphorylation may be critical in FcgammaRI (显示 FCGR1A 抗体)-dependent endocytosis/phagocytosis that may be regulated by LILRB4 by triggering dephosphorylation of key signalling proteins.

  3. ILT3 may functionally contribute to a regulatory network controlling tumor progression by suppressing the Akt (显示 AKT1 抗体) pathway.

  4. The ILT3 PBs (显示 TSPO 抗体)/PCs were suggested to be developmentally equivalent based on the simultaneous generation of these populations upon activation of memory B cells in vitro ILT3 expression was found to be induced efficiently by IL-2 (显示 IL2 抗体), while IFN-alpha effectively induced ILT3 PBs (显示 TSPO 抗体)/PCs in vitro Utilizing the elevated ILT3 will support opening a new avenue for molecular markers for, pathogenic cells.

  5. this study shows that LILRB4 might have dual inhibitory and activating functions, depending on the position of the functional tyrosine residues in its immunoreceptor tyrosine-based inhibitory motifs and/or the nature of the stimuli

  6. LILRB4 expression is significantly upregulated in human masticatory mucosa during wound healing

  7. Identification of ILT4 (显示 LILRB2 抗体) as a cellular receptor for CSP (显示 DNAJC5 抗体) C4d

  8. involvement of ILT3 and ILT4 in the modulation of immune responsiveness in multiple sclerosis by both interferon and vitamin D

  9. Cyclosporine up-regulated the expression of ILT3 and ILT4 (显示 LILRB2 抗体) on natural killer cells, which influenced their cytotoxicity against tumor cells.

  10. Crystal structure of leukocyte Ig-like receptor (显示 LILRA6 抗体) LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance.

Mouse (Murine) Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4) interaction partners

  1. Targeting hepatic LILRB4 to improve its expression or activation represents a promising strategy for the treatment of non alcoholic fatty liver diseases as well as related liver and metabolic diseases

  2. Results suggest that plasma cell development from memory and marginal zone B cells, as well as subsequent antibody production, are suppressed via glycoprotein 49B (gp49B).

  3. LILRB4 can downregulate the development of pathologic allergic inflammation.

  4. receptor attenuates the number of these mature DCs and attendant IL-4 (显示 IL4 抗体)-producing lymphocytes in the lymph nodes, and accordingly, the ability of DCs to elicit pathologic Th2 pulmonary inflammation

  5. Gp49B1 is a unique inhibitory receptor that is induced in multiple lineages of innate and adaptive immune cells during an infection and controls their IFN-gamma (显示 IFNG 抗体), but not cytotoxic responses.

  6. Expression of gp49B was detected on peripheral eosinophils of control mice and on eosinophils from lungs of mice treated with RW, suggesting a role for gp49B on eosinophils in dampening allergic inflammatory responses.

  7. study reports that gp49B, is expressed on dendritic cells and downregulates cellular activity to prevent the excessive activation of T cells in vitro and in vivo

LILRB4 抗原简介

蛋白简介

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LILRB4

  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 (LILRB4) 抗体
  • leukocyte immunoglobulin like receptor B4 (LILRB4) 抗体
  • leukocyte immunoglobulin-like receptor, subfamily B, member 4A (Lilrb4a) 抗体
  • CD85K 抗体
  • gp49 抗体
  • Gp49b 抗体
  • HM18 抗体
  • ILT-3 抗体
  • ILT3 抗体
  • LIR-5 抗体
  • LIR5 抗体

Protein level used designations for LILRB4

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 , CD85 antigen-like family member K , immunoglobulin-like transcript 3 , leukocyte immunoglobulin-like receptor 5 , leukocyte immunoglobulin-like receptor subfamily B member 4 , monocyte inhibitory receptor HM18 , glycoprotein 49 B , mast cell surface glycoprotein Gp49B

GENE ID SPECIES
100587262 Nomascus leucogenys
11006 Homo sapiens
14728 Mus musculus
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