LILRB4 抗体
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北京 101111
Quick Overview for LILRB4 抗体 (ABIN7183741)
抗原
See all LILRB4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- LILRB4 Antibody
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from internal of Human LILRB4.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))
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别名
- LILRB4
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背景
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Background: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Arm J.P., J. Immunol. 159:2342-2349(1997).
Borges L., J. Immunol. 159:5192-5196(1997).
Liu W.R., Immunogenetics 51:659-669(2000).Aliases: CD85 antigen-like family member K antibody, CD85k antibody, HM18 antibody, ILT-3 antibody, ILT3 antibody, Immunoglobulin-like transcript 3 antibody, Leukocyte immunoglobulin like receptor subfamily B (with TM and ITIM domains) member 4 antibody, Leukocyte immunoglobulin-like receptor 5 antibody, Leukocyte immunoglobulin-like receptor subfamily B member 4 antibody, LILRB4 antibody, LILRB5 antibody, LIR-5 antibody, LIR5 antibody, LIRB4_HUMAN antibody, Monocyte inhibitory receptor HM18 antibody
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UniProt
- Q8NHJ6
抗原
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