LILRB4 抗体
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北京 101111
Quick Overview for LILRB4 抗体 (ABIN7115849)
抗原
See all LILRB4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- LILRB4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Leukocyte immunoglobulin-like receptor subfamily B member 4
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- LILRB4 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 4 (LILRB4))
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别名
- LILRB4
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背景
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Synonyms: Leukocyte immunoglobulin-like receptor subfamily B member 4 (B4)|CD85 antigen-like family member K|Immunoglobulin-like transcript 3 (ILT-3)|Leukocyte immunoglobulin-like receptor 5 (LIR-5)|Monocyte inhibitory receptor HM18|LILRB4|ILT3|LIR5
Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 49 kDa
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UniProt
- Q8NHJ6
抗原
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