LIMS1 抗体
(LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
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Latest Publications for our LIMS1 抗体
: "Structural basis of focal adhesion localization of LIM-only adaptor PINCH by integrin-linked kinase." in: The Journal of biological chemistry, Vol. 284, Issue 9, pp. 5836-44, (2009) (PubMed).: "The structural basis of integrin-linked kinase-PINCH interactions." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 52, pp. 20677-82, (2008) (PubMed).
: "Identification of PINCH in Schwann cells and DRG neurons: shuttling and signaling after nerve injury." in: Glia, Vol. 41, Issue 3, pp. 213-23, (2003) (PubMed).
: "The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells." in: Molecular and cellular biology, Vol. 19, Issue 3, pp. 2425-34, (1999) (PubMed).
: "Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways." in: Molecular biology of the cell, Vol. 9, Issue 12, pp. 3367-82, (1999) (PubMed).
Aliases for LIMS1 抗体
LIM zinc finger domain containing 1 (LIMS1) 抗体LIM zinc finger domain containing 1 (Lims1) 抗体
LIM and senescent cell antigen-like domains 1 (Lims1) 抗体
2310016J22Rik 抗体
4921524A02Rik 抗体
AI507642 抗体
AU021743 抗体
AW551584 抗体
C430041B13Rik 抗体
Lims1l 抗体
LIMS3 抗体
LIMS3L 抗体
PINCH 抗体
PINCH-1 抗体
PINCH1 抗体
Pinch1 抗体
RGD1560732 抗体
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