LIN28A 抗体
(Lin-28 Homolog A (C. Elegans) (LIN28A))
Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting an uridylyltransferase, leading to the terminal uridylation of pre- let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation (By similarity).
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| LIN28A 抗体 (AA 108-138) | 人, 小鼠 | 兔 Polyclonal |
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| LIN28A 抗体 (AA 93-209) | 人 | 小鼠 Monoclonal |
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| LIN28A 抗体 (N-Term) | 人, Cow, 犬, Pig, 绵羊 | 兔 Polyclonal |
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| LIN28A 抗体 (AA 3-209) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| LIN28A 抗体 | 人 | 小鼠 Monoclonal |
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| LIN28A 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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| LIN28A 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| LIN28A 抗体 (C-Term) | 人, 小鼠 | 兔 Polyclonal |
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| LIN28A 抗体 (AA 142-209) | 人 | 兔 Polyclonal |
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| LIN28A 抗体 (AA 1-209) | 人 | 兔 Polyclonal |
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| Recombinant LIN28A 抗体 | 人 | 兔 Monoclonal |
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| LIN28A 抗体 (pSer134) | 人 | 兔 Polyclonal |
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| LIN28A 抗体 (AA 1-209) | 人 | 兔 Polyclonal |
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| LIN28A 抗体 (AA 1-209) | 人 | 小鼠 Polyclonal |
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| LIN28A 抗体 (AA 108-138) | 人, 小鼠 | 兔 Polyclonal |
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| LIN28A 抗体 (AA 65-160) | 人 | 兔 Polyclonal |
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| LIN28A 抗体 (AA 85-119) | 斑马鱼 | 兔 Polyclonal |
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| LIN28A 抗体 (N-Term) | 人 | 兔 Polyclonal |
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| LIN28A 抗体 | 人 | 兔 Polyclonal |
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| LIN28A 抗体 (pSer134) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB14827
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 108-138
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
2 references - 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 6D1F9
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- AA 93-209
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- 适用
- 人, Cow, 犬, Pig, 绵羊
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 3-209
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 55CT58-12-1
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB14266
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 168-198, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB51168
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 177-210, C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 142-209
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-209
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 质量等级
- KD Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 25GB2520
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- IF (Immunofluorescence: 有验证图片)
- DB (Dot Blot: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB18937
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- pSer134
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-209
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-209
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 108-138
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 65-160
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 斑马鱼
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB53165
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 85-119
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB51185
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 22-56, N-Term
Primary Antibody
- IF (Immunofluorescence: 有验证图片)
- DB (Dot Blot: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- pSer134
Latest Publications for our LIN28A 抗体
: "Cancer stem-like cells can be induced through dedifferentiation under hypoxic conditions in glioma, hepatoma and lung cancer." in: Cell death discovery, Vol. 3, pp. 16105, (2017) (PubMed).
: "A Rapid Induction Mechanism for Lin28a in Trophic Responses." in: Molecular cell, Vol. 65, Issue 3, pp. 490-503.e7, (2017) (PubMed).
: "Organoid models of human and mouse ductal pancreatic cancer. ..." in: Cell, Vol. 160, Issue 1-2, pp. 324-38, (2015) (PubMed).
: "Vascular gene expression and phenotypic correlation during differentiation of human embryonic stem cells." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 232, Issue 2, pp. 487-97, (2005) (PubMed).
: "Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells." in: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9198-208, (2005) (PubMed).
: "A Rapid Induction Mechanism for Lin28a in Trophic Responses." in: Molecular cell, Vol. 65, Issue 3, pp. 490-503.e7, (2017) (PubMed).
: "Organoid models of human and mouse ductal pancreatic cancer. ..." in: Cell, Vol. 160, Issue 1-2, pp. 324-38, (2015) (PubMed).
: "Vascular gene expression and phenotypic correlation during differentiation of human embryonic stem cells." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 232, Issue 2, pp. 487-97, (2005) (PubMed).
: "Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells." in: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9198-208, (2005) (PubMed).
Aliases for LIN28A 抗体
lin-28 homolog A (LIN28A) 抗体lin-28 homolog A (C. elegans) (Lin28a) 抗体
lin-28 homolog A S homeolog (lin28a.S) 抗体
lin-28 homolog A (C. elegans) (lin28a) 抗体
lin-28 homolog A (Lin28a) 抗体
lin-28 homolog A (lin28a) 抗体
AL024421 抗体
CSDD1 抗体
csdd1 抗体
ENSMUSG00000070700 抗体
Gm10299 抗体
LIN-28 抗体
Lin-28 抗体
lin-28 抗体
lin-28A 抗体
LIN28 抗体
Lin28 抗体
lin28 抗体
RGD1566408 抗体
sb:cb650 抗体
Tex17 抗体
ZCCHC1 抗体
zcchc1 抗体
zgc:55584 抗体
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