Kruppel-Like Factor 17 蛋白 (KLF17)

Transcription repressor that binds to the promoter of target genes and prevents their expression. 再加上,我们可以发KLF17 抗体 (63)KLF17 试剂盒 (12)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
KLF17 128209 Q5JT82
KLF17 75753 Q8CFA7
大鼠 KLF17 KLF17 298449  
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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酵母菌 野猪 His tag   1 mg Log in to see 60至71个工作日
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KLF17 蛋白 by Origin and Source

Origin 在表达 标记
Human

Mouse (Murine)

更多Kruppel-Like Factor 17 (KLF17)互动伙伴

Xenopus laevis Kruppel-Like Factor 17 (KLF17) interaction partners

  1. Data suggest that Neptune is a new member of hatching gland specifier and plays a physiological role in determination and specification of multiple lineages derived from the NPB region.

Human Kruppel-Like Factor 17 (KLF17) interaction partners

  1. Low Expressions of KLF17 is associated with lung adenocarcinoma.

  2. Suggest that KLF17 inhibits esophageal carcinoma development and may serve as a potential therapeutic target.

  3. Enhanced KLF17 expression sensitizes ERalpha (显示 ESR1 蛋白)-positive breast cancer cells to endocrine therapy.KLF17-ERalpha (显示 ESR1 蛋白) interaction plays a potential role in inhibition of ERalpha (显示 ESR1 蛋白)-dependent breast cancer progression.

  4. KLF17 empowers TGF-beta (显示 TGFB1 蛋白)/Smad (显示 SMAD1 蛋白) signaling by targeting Smad3 (显示 SMAD3 蛋白)-dependent pathway to suppress tumor growth and metastasis during cancer progression.

  5. Tumor-suppressive p53 (显示 TP53 蛋白) signaling is critical for KLF17 to inhibit cancer metastasis in Non-small Cell Lung Cancer.

  6. A small subset of Myoepithelial tumors harbor FUS (显示 FUS 蛋白) rearrangements, two thirds of them being associated with KLF17 fusion.

  7. In this review, we focus on the functions, roles, and regulatory networks of these five KLFs in HCC (显示 FAM126A 蛋白), summarize key pathways, and propose areas for further investigation

  8. The reduced expression of KLF17 promoted the motility and proliferation ability of TPC1 (显示 TPCN1 蛋白) cells by altering the expression of tight junction protein 1 (显示 TJP1 蛋白) and Snai1 (显示 SNAI1 蛋白), and activating the AKT (显示 AKT1 蛋白) pathway by upregulating inhibitor of DNA binding 1 (显示 ID1 蛋白).

  9. mutant p53 (显示 TP53 蛋白) enhances cancer progression by inhibiting KLF17 expression in invasive breast carcinoma cells

  10. The reduced expression of KLF17 protein in gastric cancer was correlated with tumor size, pN stage and lymphovascular invasion and was an independent predictor for poor survival in patients undergoing surgery for gastric cancer.

Mouse (Murine) Kruppel-Like Factor 17 (KLF17) interaction partners

  1. ZFP393 functions as a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development

  2. demonstrate that KLF17 expression is significantly downregulated in primary human breast cancer samples and that the combined expression pattern of KLF17 and Id1 (显示 ID1 蛋白) can serve as a potential biomarker for lymph node metastasis in breast cancer

蛋白简介KLF17

蛋白简介

Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity).

Gene names and symbols associated with Kruppel-Like Factor 17 蛋白 (KLF17)

  • Kruppel-like factor 17 L homeolog (klf17.L)
  • Kruppel like factor 17 (KLF17)
  • Kruppel-like factor 17 (klf17)
  • Kruppel-like factor 17 (Klf17)
  • Kruppel like factor 17 (Klf17)
  • 7420700M05Rik 蛋白
  • AA420409 蛋白
  • AU043468 蛋白
  • C85123 蛋白
  • D4Ertd561e 蛋白
  • Gzf 蛋白
  • neptune 蛋白
  • rp4-675g8.1 蛋白
  • Zfp393 蛋白
  • ZNF393 蛋白

Protein level used designations for Kruppel-Like Factor 17 蛋白 (KLF17)

Kruppel-like factor 17 , Kruppel-like transcription factor neptune , novel kruppel-like factor family protein , krueppel-like factor 17-like , Krueppel-like factor 17 , novel zinc-finger protein , zinc finger protein 393 , germ cell specific zinc finger protein , germ cell-specific zinc finger protein

GENE ID SPECIES
398243 Xenopus laevis
702810 Macaca mulatta
734094 Xenopus (Silurana) tropicalis
100436573 Pongo abelii
100599780 Nomascus leucogenys
128209 Homo sapiens
75753 Mus musculus
298449 Rattus norvegicus
100302639 Sus scrofa
516413 Bos taurus
100725519 Cavia porcellus
101108444 Ovis aries
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