KLHL12 蛋白
(Kelch-Like 12 (Drosophila) (KLHL12))
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). As part of the BCR(KLHL12) complex, also acts as a negative regulator of the Wnt signaling pathway by mediating ubiquitination and subsequent proteolysis of DVL3 (By similarity).
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custom-made
KLHL12
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
KLHL12
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for KLHL12 蛋白
Ski2 like RNA helicase (SKIV2L) 蛋白kelch like family member 12 L homeolog (klhl12.L) 蛋白
kelch like family member 12 (KLHL12) 蛋白
kelch-like family member 12 (klhl12) 蛋白
kelch-like 12 (Klhl12) 蛋白
kelch-like family member 12 (Klhl12) 蛋白
C3ip1 蛋白
C3IP1 蛋白
DKIR 蛋白
hDKIR 蛋白
wu:fi60g03 蛋白
zgc:92570 蛋白
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