KLHL3 蛋白
(Kelch-Like 3 (KLHL3))
This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D)\; a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012].
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custom-made
KLHL3
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
KLHL3
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
KLHL3
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
ELISA, WB
Aliases for KLHL3 蛋白
kelch like family member 3 (KLHL3) 蛋白kelch-like 3 (Klhl3) 蛋白
kelch-like family member 3 (Klhl3) 蛋白
7530408C15Rik 蛋白
AI430941 蛋白
EG627648 蛋白
PHA2D 蛋白
RGD1565218 蛋白
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