Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 2 蛋白 (KIR3DL2)

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. 再加上,我们可以发KIR3DL2 抗体 (44)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
KIR3DL2 3812 P43630
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
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大肠杆菌(E. Coli) His tag,GST tag 100 μg Log in to see 15至18个工作日
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Baculovirus infected Insect Cells hIgG-His-tag   0.5 mg Log in to see 13至16个工作日
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大肠杆菌(E. Coli) 非结合性   100 μg Log in to see 11至18个工作日
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KIR3DL2 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, , ,

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Human Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 2 (KIR3DL2) interaction partners

蛋白简介KIR3DL2

蛋白简介

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the 'framework' loci that is present on all haplotypes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with KIR3DL2

  • killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 (KIR3DL2)
  • CD158K 蛋白
  • NKAT-4 蛋白
  • NKAT4 蛋白
  • NKAT4B 蛋白
  • p140 蛋白

Protein level used designations for KIR3DL2

CD158 antigen-like family member K , KIR antigen 3DL2 , MHC class I NK cell receptor , killer Ig receptor , killer cell immunoglobulin-like receptor 3DL2 , killer cell immunoglobulin-like receptor KIR3DL2 , natural killer cell inhibitory receptor , natural killer-associated transcript 4 , p70 NK receptor CL-5 , p70 killer cell inhibitory receptor , p70 natural killer cell receptor clone CL-5

GENE ID SPECIES
3812 Homo sapiens
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