anti-Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 (IRAK1BP1) 抗体

Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. 再加上,我们可以发Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 蛋白 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
IRAK1BP1 134728 Q5VVH5
IRAK1BP1 65099 Q9ESJ7
IRAK1BP1    
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB Host: Rabbit <br /> Target Name: Irak1bp1 <br /> Sample Tissue: Mouse Testis lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 IHC (p) IHC-P Image IRAK1BP1 antibody [N1C3] detects IRAK1BP1 protein at cytoplasm on human placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. IRAK1BP1 antibody [N1C3] , dilution: 1:100. 100 μL Log in to see 3至4个工作日
$466.18
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非结合性 IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-SIMPL / IRAK1BP1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μL Log in to see 11至14个工作日
$484.00
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非结合性 IF (p), IHC (p), WB Mouse brain lysates probed with IRAK1BP1 Polyclonal Antibody, Unconjugated  at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C. 100 μL Log in to see 3至7个工作日
$306.90
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非结合性 IHC, IHC (p) Immunohistochemistry-Paraffin: IRAK1BP1 Antibody ) diluted at 1:500. Immunohistochemistry-Paraffin: IRAK1BP1 Antibody  dilution: 1:100. 0.1 mL Log in to see 8至11个工作日
$444.19
详细
非结合性 IHC, IHC (p) Immunohistochemistry-Paraffin: IRAK1BP1 Antibody [NBP2-34019] - cerebral cortex Immunohistochemistry: IRAK1BP1 Antibody [NBP2-34019] - Immunohistochemical staining of human stomach, upper shows distinct cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日
$491.63
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Alexa Fluor 350 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
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Alexa Fluor 488 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
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Alexa Fluor 555 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
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Alexa Fluor 594 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
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更多抗Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1的相互作用对抗体

Human Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 (IRAK1BP1) interaction partners

  1. Together, these studies reveal that phosphorylation of the SIMPL protein plays a critical role in SIMPL regulation by affecting both SIMPL subcellular localization and the p65 (显示 GORASP1 抗体) coactivator function of SIMPL.

Mouse (Murine) Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 (IRAK1BP1) interaction partners

  1. SIMPL functions as a TNFalpha (显示 TNF 抗体)-dependent p65 (显示 NFkBP65 抗体) co-activator by facilitating the recruitment of MED1 (显示 MBD4 抗体) to p65 (显示 NFkBP65 抗体) containing transcriptional complexes to control the expression of a subset of TNFalpha (显示 TNF 抗体)-induced genes.

  2. IRAK1BP1 functions through its effects on NF-kappaB (显示 NFKB1 抗体) as a molecular switch to bias innate immune pathways toward the resolution of inflammation

  3. Signals transduced through the tumor necrosis factor-alpha-tumor necrosis factor (显示 TNF 抗体) -receptor I-SIMPL(substrate that interacts with mouse pelle (显示 IRAK1 抗体)-like kinase) pathway support hematopoietic progenitor cell survival, growth and differentiation

  4. TNF-alpha (显示 TNF 抗体) activation of NF-kappaB (显示 NFKB1 抗体) dependent-gene expression requires nuclear relocalization of p65 (显示 NFkBP65 抗体) as well as nuclear relocalization of SIMPL, generating a TNF-alpha (显示 TNF 抗体)-specific induction of gene expression.

  5. Hsp70/Hsc70 bind the intrinsically disordered amino-terminal region of SIMPL to stabilize the protein and thereby regulate its activity.

  6. IRAK1BP1 regulates transcription of a specific subset of Toll (显示 TLR4 抗体)-like receptor responsive genes, producing an overall antiinflammatory profile

Interleukin-1 Receptor-Associated Kinase 1 Binding Protein 1 (IRAK1BP1) 抗原简介

蛋白简介

Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity (By similarity).

Gene names and symbols associated with IRAK1BP1

  • interleukin 1 receptor associated kinase 1 binding protein 1 (IRAK1BP1) 抗体
  • interleukin-1 receptor-associated kinase 1 binding protein 1 (Irak1bp1) 抗体
  • interleukin-1 receptor-associated kinase 1 binding protein 1 (irak1bp1) 抗体
  • 4921528N06Rik 抗体
  • Aabp3 抗体
  • AI851240 抗体
  • Aip70 抗体
  • Simpl 抗体
  • zgc:112481 抗体

Protein level used designations for IRAK1BP1

interleukin-1 receptor-associated kinase 1 binding protein 1 , ActA binding protein 3 , interleukin-1 receptor-associated kinase 1-binding protein 1 , Acta binding protein 3 , Acta-binding protein 70 , Plk-interacting protein , signaling molecule that associates with the mouse pelle-like kinase , interleukin-1 receptor-associated kinase 1-binding protein 1 homolog

GENE ID SPECIES
100229738 Taeniopygia guttata
100352510 Oryctolagus cuniculus
134728 Homo sapiens
65099 Mus musculus
553809 Danio rerio
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