Use your antibodies-online credentials, if available.
The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. 再加上，我们可以发IL27 抗体 (171) 和 IL27 试剂盒 (58)和数多这个蛋白质的别的产品。
Showing 10 out of 26 products:
Human IL27 Protein expressed in Wheat germ - ABIN1307800
Di Meo, Airoldi, Sorrentino, Zorzoli, Esposito, Di Carlo: Interleukin-30 expression in prostate cancer and its draining lymph nodes correlates with advanced grade and stage. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014
Show all 2 Pubmed References
IL-27 was down-regulated in the malignant Middle Cerebral Artery Infarction.
IL-27 may be involved in the development of coronary artery lesions in acute Kawasaki disease.
Hepatitis B virus infection can lead to overexpression of interleukin-27 gene in liver transplant patients.
this study indicates that IL-27 secreted by cervical carcinoma cells restricts the angiogenesis in a paracrine manner in the pathogenesis of cervical cancer
IL-27 signaling (IL-27 and its receptor) may be involved in the pathogenesis of HIV infection and immune reconstitution in HIV/AIDS patients who underwent HAART. IL-27 may exert effects through regulating Th1 (显示 TH1L 蛋白) / Th2 ratio.
This study provides additional evidence that IL-27 may contribute to autoimmune processes in MS patients.
this study shows that IL-27 regulates the adherence, proliferation, and migration of placenta-derived mesenchymal stromal cells and enhances their regulatory effects on Th1 (显示 TH1L 蛋白) and Th2 subset generations
This study failed to find an association between common variants in the functional region of IL27 and coronary artery disease in a Chinese Han population
Data point out to a broad set of activities shared by IL-27 and IFN-gamma (显示 IFNG 蛋白), which are dependent on the common activation of the STAT1 (显示 STAT1 蛋白) pathway. These data add further explanation to the anti-tumor activity of IL-27 and also to its dual role in immune regulation
The current meta-analysis suggests that IL-27 -964A/G polymorphism might enhance cancer risk. However, large-scale and well-designed studies are still needed to confirm the result of our meta-analysis
IFN-gamma (显示 IFNG 蛋白) induces IL-30 production which suppresses IFN-gamma (显示 IFNG 蛋白) mediated liver inflammation.
IL-27 signaling in Foxp3 (显示 FOXP3 蛋白)(+) Tregs essential for Tregs to control autoimmune inflammation in the central nervous system
this study has revealed an important role of thymic dendritic cells-derived IL-27 in the regulation of the phenotypic maturation of CD4 (显示 CD4 蛋白)(+) single positive thymocytes.
TTP (显示 ZFP36 蛋白), encoded by Zfp36 (显示 ZFP36 蛋白), degrades p28 (显示 GSTO1 蛋白) to inhibit IL-27 production by macrophages and is thereby a negative regulator of the antitumour response.
these data infer that endopeptidase mediated gliadin degradation by macrophages and concomitant IL-27 production drive differentiation of splenic gliadin-specific Tr1 (显示 TXNRD1 蛋白)-like cells in celiac disease
endogenous levels of IL-27 affected the oncogenic properties of mutant p53 (显示 TP53 蛋白) in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.
Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin (显示 LTF 蛋白).
Serum IL-27 levels and cardiac IL-27 mRNA expression were significantly increased after LPS (显示 TLR4 蛋白) injection compared with control specimens.
these findings highlight critical roles for IFN-gamma (显示 IFNG 蛋白) and IL-27 in the mechanism of respiratory syncytial virus-induced exacerbation
The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
, IL-27 p28 subunit
, IL-27 subunit alpha
, interleukin 30
, interleukin-27 subunit alpha
, interluekin 27
, interleukin 27 p28 subunit