Interleukin 27 蛋白 (IL27)

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. 再加上,我们可以发IL27 抗体 (171)IL27 试剂盒 (58)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
IL27 53342 Q8TAD2
IL27 365368  
IL27 246779 Q8K3I6
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Showing 10 out of 26 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
CHO Cells His tag 10 μg Log in to see 20至21个工作日
$250.80
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人细胞 小鼠 His tag 10 μg Log in to see 20至21个工作日
$250.80
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大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$5,465.26
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大肠杆菌(E. Coli) 小鼠 非结合性 100 μg Log in to see 1至2个工作日
$638.00
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大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$5,465.26
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大肠杆菌(E. Coli) 小鼠 His tag 100 μg Log in to see 15至18个工作日
$784.00
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大肠杆菌(E. Coli) 大鼠 His tag 100 μg Log in to see 15至18个工作日
$800.00
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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大肠杆菌(E. Coli) 小鼠 非结合性   1 mg Log in to see 2至3个工作日
$6,760.00
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大肠杆菌(E. Coli) 小鼠 非结合性 Lane 1: non-reducing conditions Lane 2: reducing conditions 10 μg Log in to see 11至12个工作日
$220.80
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IL27 蛋白 by Origin and Source

Origin 在表达 标记
Human , , , ,
,
Rat (Rattus)

Mouse (Murine) , ,

引用最多的IL27 蛋白

  1. Human IL27 Protein expressed in Wheat germ - ABIN1307800 : Di Meo, Airoldi, Sorrentino, Zorzoli, Esposito, Di Carlo: Interleukin-30 expression in prostate cancer and its draining lymph nodes correlates with advanced grade and stage. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014 (PubMed)
    Show all 2 Pubmed References

更多Interleukin 27 (IL27)互动伙伴

Human Interleukin 27 (IL27) interaction partners

  1. IL-27 was down-regulated in the malignant Middle Cerebral Artery Infarction.

  2. IL-27 may be involved in the development of coronary artery lesions in acute Kawasaki disease.

  3. Hepatitis B virus infection can lead to overexpression of interleukin-27 gene in liver transplant patients.

  4. this study indicates that IL-27 secreted by cervical carcinoma cells restricts the angiogenesis in a paracrine manner in the pathogenesis of cervical cancer

  5. IL-27 signaling (IL-27 and its receptor) may be involved in the pathogenesis of HIV infection and immune reconstitution in HIV/AIDS patients who underwent HAART. IL-27 may exert effects through regulating Th1 (显示 TH1L 蛋白) / Th2 ratio.

  6. This study provides additional evidence that IL-27 may contribute to autoimmune processes in MS patients.

  7. this study shows that IL-27 regulates the adherence, proliferation, and migration of placenta-derived mesenchymal stromal cells and enhances their regulatory effects on Th1 (显示 TH1L 蛋白) and Th2 subset generations

  8. This study failed to find an association between common variants in the functional region of IL27 and coronary artery disease in a Chinese Han population

  9. Data point out to a broad set of activities shared by IL-27 and IFN-gamma (显示 IFNG 蛋白), which are dependent on the common activation of the STAT1 (显示 STAT1 蛋白) pathway. These data add further explanation to the anti-tumor activity of IL-27 and also to its dual role in immune regulation

  10. The current meta-analysis suggests that IL-27 -964A/G polymorphism might enhance cancer risk. However, large-scale and well-designed studies are still needed to confirm the result of our meta-analysis

Mouse (Murine) Interleukin 27 (IL27) interaction partners

  1. IFN-gamma (显示 IFNG 蛋白) induces IL-30 production which suppresses IFN-gamma (显示 IFNG 蛋白) mediated liver inflammation.

  2. IL-27 signaling in Foxp3 (显示 FOXP3 蛋白)(+) Tregs essential for Tregs to control autoimmune inflammation in the central nervous system

  3. this study indicates that IL-27 secreted by cervical carcinoma cells restricts the angiogenesis in a paracrine manner in the pathogenesis of cervical cancer

  4. this study has revealed an important role of thymic dendritic cells-derived IL-27 in the regulation of the phenotypic maturation of CD4 (显示 CD4 蛋白)(+) single positive thymocytes.

  5. TTP (显示 ZFP36 蛋白), encoded by Zfp36 (显示 ZFP36 蛋白), degrades p28 (显示 GSTO1 蛋白) to inhibit IL-27 production by macrophages and is thereby a negative regulator of the antitumour response.

  6. these data infer that endopeptidase mediated gliadin degradation by macrophages and concomitant IL-27 production drive differentiation of splenic gliadin-specific Tr1 (显示 TXNRD1 蛋白)-like cells in celiac disease

  7. endogenous levels of IL-27 affected the oncogenic properties of mutant p53 (显示 TP53 蛋白) in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.

  8. Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin (显示 LTF 蛋白).

  9. Serum IL-27 levels and cardiac IL-27 mRNA expression were significantly increased after LPS (显示 TLR4 蛋白) injection compared with control specimens.

  10. these findings highlight critical roles for IFN-gamma (显示 IFNG 蛋白) and IL-27 in the mechanism of respiratory syncytial virus-induced exacerbation

Pig (Porcine) Interleukin 27 (IL27) interaction partners

  1. The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).

蛋白简介IL27

蛋白简介

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Gene names and symbols associated with Interleukin 27 蛋白 (IL27)

  • interleukin 17D (IL17D)
  • interleukin 27 (IL27)
  • interleukin 27 (Il27)
  • IL-17D 蛋白
  • IL-22 蛋白
  • IL-27 蛋白
  • IL-27A 蛋白
  • IL-27p28 蛋白
  • IL27 蛋白
  • IL27A 蛋白
  • IL27p28 蛋白
  • Il30 蛋白
  • p28 蛋白
  • RGD1561420 蛋白

Protein level used designations for Interleukin 27 蛋白 (IL27)

interleukin 27 , interleukin-17D , interleukin-27 , IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha , interluekin 27 , interleukin 27 p28 subunit , p28

GENE ID SPECIES
53342 Homo sapiens
246778 Homo sapiens
365368 Rattus norvegicus
607880 Canis lupus familiaris
614927 Bos taurus
737725 Pan troglodytes
246779 Mus musculus
493187 Sus scrofa
100349321 Oryctolagus cuniculus
100724612 Cavia porcellus
101122495 Ovis aries
101093822 Felis catus
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