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Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. 再加上，我们可以发GDF15 试剂盒 (88) 和 GDF15 蛋白 (34)和数多这个蛋白质的别的产品。
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Human Polyclonal GDF15 Primary Antibody for IHC, IHC (p) - ABIN4313803
Tabrizi, Kalloger, Köbel, Cipollone, Roskelley, Mehl, Gilks: Primary ovarian mucinous carcinoma of intestinal type: significance of pattern of invasion and immunohistochemical expression profile in a series of 31 cases. in International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2010
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Mouse (Murine) Polyclonal GDF15 Primary Antibody for IHC - ABIN966198
Iguchi, Chrysovergis, Lee, Baek, Langenbach, Eling: A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2. in Cancer letters 2009
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Mouse (Murine) Polyclonal GDF15 Primary Antibody for IHC - ABIN966197
Cekanova, Lee, Donnell, Sukhthankar, Eling, Fischer, Baek: Nonsteroidal anti-inflammatory drug-activated gene-1 expression inhibits urethane-induced pulmonary tumorigenesis in transgenic mice. in Cancer prevention research (Philadelphia, Pa.) 2009
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Mouse (Murine) Polyclonal GDF15 Primary Antibody for IHC - ABIN966196
Ding, Mracek, Gonzalez-Muniesa, Kos, Wilding, Trayhurn, Bing: Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. in Endocrinology 2009
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Human Polyclonal GDF15 Primary Antibody for IF (p), IHC (p) - ABIN704561
Ruan, Li, Nie, Zhou, Zou: Differential expression of glycoprotein non-metastatic melanoma protein B (GPNMB) involved in trichostatin A-induced apoptosis in gastric cancer. in International journal of clinical and experimental medicine 2015
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Human Polyclonal GDF15 Primary Antibody for ELISA, WB - ABIN269826
Comitato, Nesaretnam, Leoni, Ambra, Canali, Bolli, Marino, Virgili: A novel mechanism of natural vitamin E tocotrienol activity: involvement of ERbeta signal transduction. in American journal of physiology. Endocrinology and metabolism 2009
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Mouse (Murine) Polyclonal GDF15 Primary Antibody for ELISA, WB - ABIN1043801
Baek, Eling: Changes in gene expression contribute to cancer prevention by COX inhibitors. in Progress in lipid research 2006
In patients with chronic obstructive pulmonary disease, high levels of GDF15 were independently associated with a higher yearly rate of exacerbations, higher mortality and increased decline in both FEV1 and FVC.
Data suggested NAG-1 protein as a crucial mediator of epithelial ovarian cancer (EOC) progression and resistance to the standard first-line chemotherapy against EOC, particularly in MyD88 (显示 MYD88 抗体)-positive ovarian cancer stem-like cells.
The GDF-15 gene rs1804826G/T polymorphism and sGDF-15 levels are associated with ischemic stroke in the Chinese population.
NSAID-activated gene 1 (NAG-1) has been assessed for its involvement in cellular integrity and pathogenesis in mucosal inflammation and carcinogenesis. [review]
showed association between high level of GDF-15, determined at the first 24 hours after acute coronary syndrome, and chronic heart failure progression after 12 months.
Results provide evidence that GDF15 contributes to the cancer-associated fibroblasts-mediated chemoprotection of AML (显示 RUNX1 抗体) cells.
serum GDF15 was not altered in the first trimester in women destined to develop late-onset preeclampsia.
even very small amounts of contaminating TGF-b in purified protein batches may influence the experimental results given that receptors for TGF-b are present. When we attempted to characterize possible receptors for the TGF-b superfamily ligand GDF15, striking similarities between GDF15-induced activities and known TGF-b activities were found.
In ever-smokers with COPD (显示 ARCN1 抗体) free of clinical CVD, GDF-15 contributes independently to subclinical coronary atherosclerosis. TRIAL REGISTRATION: ClinicalTrials.gov, NCT00608764 . Registered 28 January 2008.
This is the first study showing that adolescent male swimmers have higher PTX3 (显示 PITX3 抗体) levels than sedentary controls and that there is a linear relationship between PTX3 (显示 PITX3 抗体) and GDF-15.
isolating GFRAL as the receptor for GDF15-induced anorexia and weight loss, the identification of a mechanistic basis for the non-homeostatic regulation of neural circuitry by a peripheral signal associated with tissue damage and stress; findings provide opportunities to develop therapeutic agents for the treatment of disorders with altered energy demand
These data suggest that GDF15 is required for IL-13 (显示 IL13 抗体)-induced improvement of glucose intolerance in mice fed an HFD.
HIF-1alpha (显示 HIF1A 抗体) and GDF15 expression are inversely related under normoxia and hyperoxia.
This is the first study defining the role of Mic-1/Gdf15 in a number of behavioural domains.
epithelial restitution was promoted by enhanced NAG-1 expression and subsequent enterocyte locomotion during the early wound-healing process
both GDF-15 and TGF-beta1 (显示 TGFB1 抗体) counteract chemokine (显示 CCL1 抗体)-induced integrin activation on neutrophils via the ALK-5 (显示 TGFBR1 抗体)/TGF-betaRII heterodimer.
GDF15 is a potent mitohormetic signal that safeguards against the onset of obesity and insulin (显示 INS 抗体) resistance.
The aim of this study was to identify the role of endogenous Gdf-15 in the MPTP (显示 PTPN2 抗体) (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease (PD) by comparing Gdf-15 (+/+) and Gdf-15 (-/-) mice.
The results of this study indicated the importance of Gdf-15 in promoting survival of DAergic neurons and regulating the inflammatory response post 6-OHDA lesion.
endogenous Growth/differentiation factor-15 is beneficial for axon regeneration following sciatic nerve crush
Bone morphogenetic proteins (e.g., BMP9\; MIM 605120) are members of the transforming growth factor-beta (see TGFB1\; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.
growth differentiation factor 15
, NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1
, NSAID-activated gene 1 protein
, NSAID-regulated gene 1 protein
, growth/differentiation factor 15
, macrophage inhibitory cytokine 1
, placental TGF-beta
, placental bone morphogenetic protein
, prostate differentiation factor
, macrophage inhibiting cytokine-1