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GDF15 抗体 (N-Term)

GDF15 适用: 人 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257251
发货至: 中国
  • 抗原 See all GDF15 抗体
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    抗原表位
    • 17
    • 15
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    • 5
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    N-Term
    适用
    • 88
    • 30
    • 23
    • 1
    • 1
    宿主
    • 85
    • 12
    • 3
    • 1
    克隆类型
    • 85
    • 15
    • 1
    多克隆
    标记
    • 52
    • 15
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    This GDF15 antibody is un-conjugated
    应用范围
    • 86
    • 53
    • 35
    • 16
    • 13
    • 13
    • 9
    • 7
    • 5
    • 5
    • 3
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    GDF15 Antibody detects endogenous levels of total GDF15.
    预测反应
    Pig,Bovine,Sheep,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human GDF15, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product GDF15 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    GDF15 (Growth Differentiation Factor 15 (GDF15))
    别名
    GDF15 (GDF15 产品)
    别名
    GDF15 antibody, GDF-15 antibody, MIC-1 antibody, MIC1 antibody, NAG-1 antibody, PDF antibody, PLAB antibody, PTGFB antibody, SBF antibody, growth differentiation factor 15 antibody, GDF15 antibody, Gdf15 antibody
    背景

    Description: Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099, PubMed:23468844, PubMed:29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes, inhibits growth hormone signaling (By similarity).

    Gene: GDF15

    分子量
    37 kDa
    基因ID
    9518
    UniProt
    Q99988
    途径
    SARS-CoV-2 Protein Interactome
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