Growth Arrest-Specific 8 蛋白 (GAS8)

GAS8 includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. 再加上,我们可以发GAS8 抗体 (33)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
GAS8 104346 Q60779
GAS8 361438 Q499U4
GAS8 2622 O95995
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GAS8 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine)

Rat (Rattus)

Human

更多Growth Arrest-Specific 8 (GAS8)互动伙伴

Zebrafish Growth Arrest-Specific 8 (GAS8) interaction partners

  1. results demonstrate a requirement for the dynein regulatory complex in vertebrates and show that cilia-driven flow is a key epigenetic factor in controlling otolith biomineralization

Mouse (Murine) Growth Arrest-Specific 8 (GAS8) interaction partners

  1. Here, we generate the first mouse with a Gas8 mutation and show that it causes severe Primary Ciliary Dyskinesia (PCD (显示 PCBD1 蛋白))phenotypes; however, there were no overt Hh pathway phenotypes. In addition, we identified two human patients with missense variants in Gas8

  2. results identify Gas8 as a positive regulator of Hh signaling that cooperates with GRK2 (显示 ADRBK1 蛋白) to control Smo signaling

  3. Gas11, the mammalian trypanin/PF2 homologue, associates with microtubules in vitro and in vivo.

  4. Gas8 was specifically interacted with the GTP (显示 AK3 蛋白)-bound form of Rab3B (显示 RAB3B 蛋白) and co-localized with Rab3B (显示 RAB3B 蛋白) at the Golgi in NIH 3T3 cells

Human Growth Arrest-Specific 8 (GAS8) interaction partners

  1. Study identifies bi-allelic loss-of-function mutations in GAS8 as a cause for primary ciliary dyskinesia, and unveils the key importance of the protein encoded by this gene in N-DRC (显示 FECH 蛋白) integrity and in the proper alignment of axonemal microtubules in humans.

  2. Here, we generate the first mouse with a Gas8 mutation and show that it causes severe Primary Ciliary Dyskinesia (PCD)phenotypes; however, there were no overt Hh pathway phenotypes. In addition, we identified two human patients with missense variants in Gas8

  3. Loss-of-Function GAS8 Mutations Cause Primary Ciliary Dyskinesia and Disrupt the Nexin-Dynein Regulatory Complex.

  4. A two-hybrid screen for proteins that interact with NS1 from influenza A yielded growth arrest-specific protein 8. Gas8 associated with NS1 in vitro and in vivo.

蛋白简介GAS8

蛋白简介

This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene.

Gene names and symbols associated with Growth Arrest-Specific 8 蛋白 (GAS8)

  • Growth arrest specific protein 8 (Gas8)
  • growth arrest-specific 8 (gas8)
  • growth arrest specific 8 (GAS8)
  • growth arrest specific 8 S homeolog (gas8.S)
  • growth arrest specific 8 (gas8)
  • growth arrest specific 8 (Gas8)
  • CG14271 蛋白
  • Dmel\\CG14271 蛋白
  • GAS11 蛋白
  • MGC114774 蛋白
  • wu:fb93e12 蛋白
  • zgc:66271 蛋白

Protein level used designations for Growth Arrest-Specific 8 蛋白 (GAS8)

CG14271-PB , Gas8-PB , growth arrest specific protein 8 , growth arrest-specific protein 8 , growth arrest-specific 8 , GAS-11 , GAS-8 , beta growth arrest specific protein 11 , growth arrest specific 11 , growth arrest specific protein 11 , growth arrest-specific protein 11 , growth arrest-specific 11

GENE ID SPECIES
31321 Drosophila melanogaster
323260 Danio rerio
454330 Pan troglodytes
735136 Xenopus laevis
100127615 Xenopus (Silurana) tropicalis
104346 Mus musculus
361438 Rattus norvegicus
2622 Homo sapiens
415858 Gallus gallus
608663 Canis lupus familiaris
504318 Bos taurus
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