GANP 蛋白
(Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. [provided by RefSeq, Jul 2008].
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Latest Publications for our GANP 蛋白
: "The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia." in: Journal of immunological methods, Vol. 370, Issue 1-2, pp. 1-13, (2011) (PubMed).
Aliases for GANP 蛋白
minichromosome maintenance complex component 3 associated protein (Mcm3ap) 蛋白minichromosome maintenance complex component 3 associated protein (MCM3AP) 蛋白
minichromosome maintenance complex component 3 associated protein (mcm3ap) 蛋白
germinal-center associated nuclear protein (LOC100026233) 蛋白
GANP 蛋白
MAP80 蛋白
mKIAA0572 蛋白
SAC3 蛋白
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