G Protein-Coupled Receptor Associated Sorting Protein 1 蛋白 (GPRASP1)

GPRASP1 encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. 再加上,我们可以发G Protein-Coupled Receptor Associated Sorting Protein 1 抗体 (39)G Protein-Coupled Receptor Associated Sorting Protein 1 试剂盒 (14)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
大鼠 GPRASP1 GPRASP1 171407 Q920R4
GPRASP1 67298 Q5U4C1
GPRASP1 9737 Q5JY77
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
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CHO Cells 非结合性   50 μg Log in to see 2至3个工作日
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CHO Cells 非结合性   0.005 mg Log in to see 2至3个工作日
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GPRASP1 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine)

Human ,

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Mouse (Murine) G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1) interaction partners

  1. present the First low resolution solution structure of myostatin (显示 MSTN 蛋白)-free and myostatin (显示 MSTN 蛋白)-bound states of GASP-1 and GASP-2 (显示 WFIKKN1 蛋白)

  2. Gasp-1 overexpression resulted in increased myostatin (显示 MSTN 蛋白) expression.

  3. GASP-1 and GASP-2 (显示 WFIKKN1 蛋白) are important modulators of GDF-11 (显示 GDF11 蛋白) and MSTN (显示 MSTN 蛋白) activity in vivo.

  4. Overexpression of Gasp1 led to an increase in muscle mass observed not before day 15 of postnatal life.

  5. The pattern of behavioral deficits observed in GASP-1-deficient mice is coherent with current knowledge of the role of striatal G protein-coupled receptor(GPCR (显示 TAS1R3 蛋白))s in acquisition/expression of skilled behavior and motivation.

Human G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1) interaction partners

  1. Study demonstrated that binding of clozapine or olanzapine to the 5-HT7 receptor leads to antagonist-mediated lysosomal degradation by exposing key residues in the C-terminal tail that interact with GASP-1

  2. Data suggest that specific serine/threonine residues in DRD2 (dopamine receptor D2 (显示 DRD2 蛋白)) are involved in regulation of DRD2 (显示 DRD2 蛋白) endocytosis by GRK2 (G-protein coupled receptor kinase 2 (显示 ADRBK1 蛋白)) and GASP1.

  3. GASP1 was identified as a potential new serum and biomarker for brain, pancreatic, lung, and breast cancers, and gliomas.

  4. GASP-1 is a key regulator of the trafficking and, by extension, functional expression of GPR55 (显示 GPR55 蛋白)

  5. LIR (显示 CD300C 蛋白) was able to induce gains in 1RM and quadriceps CSA (显示 ERCC8 蛋白) similar to those observed after traditional HI. These responses may be related to the concomitant decrease in MSTN (显示 MSTN 蛋白) and increase in FLST isoforms, GASP-1, and SMAD-7 (显示 SMAD7 蛋白) mRNA gene expression.

  6. These studies identify GASP-1 as a potential new serum and tumor biomarker for breast cancer.

  7. following this endocytosis the D(3) dopamine receptors fail to recycle and are instead targeted for degradation through an interaction with the G protein-coupled receptor (GPCR (显示 TAS1R3 蛋白))-associated sorting protein-1 (GASP-1)

  8. identified a protein that binds preferentially to the cytoplasmic tail of the delta opioid receptor as a candidate heterotrimeric GTP-binding protein (G protein)-coupled receptor (显示 ADRA1A 蛋白)-associated sorting protein (GASP) [GASP]

  9. Modulation of the D2-GASP interaction is important for the functional down-regulation of D2 dopamine receptors.

蛋白简介G Protein-Coupled Receptor Associated Sorting Protein 1 (GPRASP1)

蛋白简介

This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Gene names and symbols associated with GPRASP1

  • G protein-coupled receptor associated sorting protein 1 (Gprasp1)
  • G protein-coupled receptor associated sorting protein 1 (GPRASP1)
  • 2210415K24Rik 蛋白
  • 3110031O14Rik 蛋白
  • C87852 蛋白
  • GASP 蛋白
  • GASP-1 蛋白
  • GASP1 蛋白
  • pips 蛋白

Protein level used designations for GPRASP1

G-protein coupled receptor-associated sorting protein 1 , GASP-1 , Per1 interacting protein , per1-interacting protein , G protein-coupled receptor associated sorting protein 1 , G-protein coupled receptor-associated sorting protein 1-like

GENE ID SPECIES
171407 Rattus norvegicus
465770 Pan troglodytes
480996 Canis lupus familiaris
693850 Macaca mulatta
100343091 Oryctolagus cuniculus
100398354 Callithrix jacchus
100458896 Pongo abelii
100469716 Ailuropoda melanoleuca
67298 Mus musculus
9737 Homo sapiens
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