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Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. 再加上，我们可以发C3AR1 抗体 (103) 和 C3AR1 试剂盒 (19)和数多这个蛋白质的别的产品。
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Neural crest cells are coattracted via the complement fragment C3a (显示 C3 蛋白) and its receptor C3aR, revealing an unexpected role of complement proteins in early vertebrate development.
Studies indicate that the complement response lie the active fragments, C3a (显示 C3 蛋白) and C5a, acting through their specific receptors, C3aR, C5aR1 (显示 C5AR1 蛋白) and C5aR2 to direct the cellular response to inflammation.
High C3aR1 expression is associated with acute myeloid leukemia (显示 BCL11A 蛋白)-M2.
these findings suggest a critical role for C3a (显示 C3 蛋白) through autocrine/paracrine induction of C3aR in the pathogenesis of cigarette smoke-induced sterile inflammation and provide new therapeutic targets for the treatment of emphysema.
Medulloblastoma cells express C3aR, and siRNA-mediated knockdown of C3aR inhibits proliferation of these cells in vitro.
Observed a positive correlation between the expression of anaphylatoxin-receptors C3aR and C5aR (显示 C5AR1 蛋白) with platelet activation in patients with coronary artery disease.
The obesity-induced down-regulation of complement C3 (显示 C3 蛋白) and C3aR which is specific to subcutaneous adipose tissue.
In patients with IgAN, urinary and renal C3a (显示 C3 蛋白) and C5a and renal expression of C3aR and C5aR (显示 C5AR1 蛋白) are significantly correlated with the activity and severity of renal injury.
C3aR and CD46 (显示 CD46 蛋白) activation via intrinsic generation of their respective ligands is an integral part of human Th1 (显示 TH1L 蛋白) (but not Th2) immunity.
functional regulation of C3aR by NHERFs in human mast cells
significantly decreased expression of C3aR mRNA and protein expression in placentas with preeclampsia compared to controls
The complement 3a receptor (C3aR1) participates in microglial signaling under pathological conditions and was recently shown to be activated by the neuropeptide TLQP-21.
whilst the C3aR modulates some elements of disease pathogenesis, overall it is not critical in effector responses and glomerular injury caused by autoimmunity to MPO (显示 MPO 蛋白)
study provided detailed insights into the C3aR expression pattern in immune and stromal cells under steady-state conditions
proposal that C3aR activation alters the tumor inflammatory milieu, thereby promoting tumor growth
The roles of C3, CfB (显示 CFB 蛋白), and C3a (显示 C3 蛋白) receptor in the severity of S. aureus induced septic arthritis are reported.
increased circulating lipopolysaccharide induces upregulation of complement C3a (显示 C3 蛋白) receptor on neutrophils and activation of the complement cascade.
showed that C3a (显示 C3 蛋白) receptor/C5a receptor-deficient mice developed much less severe uveitis than did control mice using all retinal examination methods
C3a (显示 C3 蛋白)/C3aR signaling during host immune response suppresses Fas (显示 FAS 蛋白) expression and caspase-3 (显示 CASP3 蛋白) activity while increasing Bcl-2 (显示 BCL2 蛋白) proto-oncogene (显示 RAB1A 蛋白) protein expression, providing protection to myeloid and lymphoid cells against L. monocytogenes-induced apoptosis.
This study indicated that C3a (显示 C3 蛋白) and C5a-mediated functions are not critical to the development of experimental autoimmune uveitis.
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity).
c3a anaphylatoxin chemotactic receptor
, C3a anaphylatoxin chemotactic receptor
, complement component 3a receptor 1
, complement component 3 receptor 1
, anaphylatoxin C3a receptor