Complement Component 3a Receptor 1 蛋白 (C3AR1)

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. 再加上,我们可以发C3AR1 抗体 (107)C3AR1 试剂盒 (16)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
C3AR1 719 Q16581
C3AR1 12267 O09047
大鼠 C3AR1 C3AR1 84007 O55197
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells 小鼠 rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50至55个工作日
$4,244.78
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大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$4,331.68
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10至12个工作日
$785.40
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小麦胚 GST tag 2 μg Log in to see 11至12个工作日
$333.33
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小麦胚 非结合性   10 μg Log in to see 11至12个工作日
$641.43
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C3AR1 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, , ,
Mouse (Murine) ,
,

更多Complement Component 3a Receptor 1 (C3AR1)互动伙伴

Zebrafish Complement Component 3a Receptor 1 (C3AR1) interaction partners

  1. Neural crest cells are coattracted via the complement fragment C3a (显示 C3 蛋白) and its receptor C3aR, revealing an unexpected role of complement proteins in early vertebrate development.

Human Complement Component 3a Receptor 1 (C3AR1) interaction partners

  1. Studies indicate that the complement response lie the active fragments, C3a (显示 C3 蛋白) and C5a, acting through their specific receptors, C3aR, C5aR1 (显示 C5AR1 蛋白) and C5aR2 to direct the cellular response to inflammation.

  2. High C3aR1 expression is associated with acute myeloid leukemia (显示 BCL11A 蛋白)-M2.

  3. these findings suggest a critical role for C3a (显示 C3 蛋白) through autocrine/paracrine induction of C3aR in the pathogenesis of cigarette smoke-induced sterile inflammation and provide new therapeutic targets for the treatment of emphysema.

  4. Medulloblastoma cells express C3aR, and siRNA-mediated knockdown of C3aR inhibits proliferation of these cells in vitro.

  5. Observed a positive correlation between the expression of anaphylatoxin-receptors C3aR and C5aR (显示 C5AR1 蛋白) with platelet activation in patients with coronary artery disease.

  6. The obesity-induced down-regulation of complement C3 (显示 C3 蛋白) and C3aR which is specific to subcutaneous adipose tissue.

  7. In patients with IgAN, urinary and renal C3a (显示 C3 蛋白) and C5a and renal expression of C3aR and C5aR (显示 C5AR1 蛋白) are significantly correlated with the activity and severity of renal injury.

  8. C3aR and CD46 (显示 CD46 蛋白) activation via intrinsic generation of their respective ligands is an integral part of human Th1 (显示 TH1L 蛋白) (but not Th2) immunity.

  9. functional regulation of C3aR by NHERFs in human mast cells

  10. significantly decreased expression of C3aR mRNA and protein expression in placentas with preeclampsia compared to controls

Mouse (Murine) Complement Component 3a Receptor 1 (C3AR1) interaction partners

  1. study provided detailed insights into the C3aR expression pattern in immune and stromal cells under steady-state conditions

  2. proposal that C3aR activation alters the tumor inflammatory milieu, thereby promoting tumor growth

  3. The roles of C3, CfB (显示 CFB 蛋白), and C3a (显示 C3 蛋白) receptor in the severity of S. aureus induced septic arthritis are reported.

  4. increased circulating lipopolysaccharide induces upregulation of complement C3a (显示 C3 蛋白) receptor on neutrophils and activation of the complement cascade.

  5. showed that C3a (显示 C3 蛋白) receptor/C5a receptor-deficient mice developed much less severe uveitis than did control mice using all retinal examination methods

  6. these findings suggest a critical role for C3a (显示 C3 蛋白) through autocrine/paracrine induction of C3aR in the pathogenesis of cigarette smoke-induced sterile inflammation and provide new therapeutic targets for the treatment of emphysema.

  7. C3a (显示 C3 蛋白)/C3aR signaling during host immune response suppresses Fas (显示 FAS 蛋白) expression and caspase-3 (显示 CASP3 蛋白) activity while increasing Bcl-2 (显示 BCL2 蛋白) proto-oncogene (显示 RAB1A 蛋白) protein expression, providing protection to myeloid and lymphoid cells against L. monocytogenes-induced apoptosis.

  8. This study indicated that C3a (显示 C3 蛋白) and C5a-mediated functions are not critical to the development of experimental autoimmune uveitis.

  9. The binding of TLQP-21 to C3AR1 not only has effects on signaling but also modulates cellular functions

  10. C3a (显示 C3 蛋白) receptor promotes viral containment in mice inoculated with vaccinia virus at sites of allergic skin inflammation.

蛋白简介C3AR1

蛋白简介

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity).

Gene names and symbols associated with C3AR1

  • C3a anaphylatoxin chemotactic receptor (c3ar1)
  • complement C3a receptor 1 (C3AR1)
  • complement component 3a receptor 1 (C3ar1)
  • complement C3a receptor 1 (C3ar1)
  • AZ3B 蛋白
  • C3a-R 蛋白
  • C3AR 蛋白
  • c3ar1 蛋白
  • HNFAG09 蛋白

Protein level used designations for C3AR1

c3a anaphylatoxin chemotactic receptor , C3AR , C3a anaphylatoxin chemotactic receptor , C3a-R , complement component 3a receptor 1 , complement component 3 receptor 1 , anaphylatoxin C3a receptor

GENE ID SPECIES
794255 Danio rerio
100136104 Oncorhynchus mykiss
100171704 Pongo abelii
466942 Pan troglodytes
716086 Macaca mulatta
100231704 Taeniopygia guttata
719 Homo sapiens
12267 Mus musculus
84007 Rattus norvegicus
100351157 Oryctolagus cuniculus
100379246 Cavia porcellus
486704 Canis lupus familiaris
540702 Bos taurus
418198 Gallus gallus
101104226 Ovis aries
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